Aliases for LOC109113861 Gene
External Ids for LOC109113861 Gene
- Entrez Gene: 109113861
This biological region is found within a region thought to be an alternative promoter of the AF4/FMR2 family member 3 (AFF3) gene on the q arm of chromosome 2. This region is a folate-sensitive fragile site and contains a CGG/CCG trinucleotide repeat. Expansions of this repeat are thought to be associated with intellectual disability. Allelic variation occurs in this region, with repeat sizes of about 3-20 observed in individuals who show no phenotypic consequences. Repeat expansions are associated with CpG hypermethylation and reduced expression of the AFF3 gene product. [provided by RefSeq, Nov 2016]
GeneCards Summary for LOC109113861 Gene
LOC109113861 (FRA2A Repeat Instability Region) is a Biological Region gene.