This region represents the proximal promoter and associated 5' regulatory elements of the hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1) gene. This sequence includes an enhancer element located in the first intron of this gene. An additional element located approximately 2.5 kb from the transcription start site binds TEA domain transcripti... See more...

Aliases for LOC109029529 Gene

Aliases for LOC109029529 Gene

  • HSD3B1 5' Regulatory Region 3

External Ids for LOC109029529 Gene

Summaries for LOC109029529 Gene

Entrez Gene Summary for LOC109029529 Gene

  • This region represents the proximal promoter and associated 5' regulatory elements of the hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (HSD3B1) gene. This sequence includes an enhancer element located in the first intron of this gene. An additional element located approximately 2.5 kb from the transcription start site binds TEA domain transcription factor 3 and GATA binding protein and may enhance gene expression in placental cells. [provided by RefSeq, Nov 2016]

GeneCards Summary for LOC109029529 Gene

LOC109029529 (HSD3B1 5' Regulatory Region) is a Biological Region gene.

Additional gene information for LOC109029529 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LOC109029529 Gene

Genomics for LOC109029529 Gene

Genomic Locations for LOC109029529 Gene

Genomic Locations for LOC109029529 Gene
chr1:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for LOC109029529 Gene

RefSeq DNA sequence for LOC109029529 Gene

No data available for GeneHancer (GH) Regulatory Elements and Cytogenetic band for LOC109029529 Gene

Proteins for LOC109029529 Gene

Post-translational modifications for LOC109029529 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC109029529 Gene

Domains & Families for LOC109029529 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LOC109029529 Gene

Function for LOC109029529 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC109029529 Gene

Localization for LOC109029529 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC109029529 Gene

Pathways & Interactions for LOC109029529 Gene

PathCards logo

SuperPathways for LOC109029529 Gene

No Data Available
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Gene Ontology (GO) - Biological Process for LOC109029529 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LOC109029529 Gene

Drugs & Compounds for LOC109029529 Gene

No Compound Related Data Available

Transcripts for LOC109029529 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LOC109029529 Gene

No ASD Table

No data available for mRNA/cDNA for LOC109029529 Gene

Expression for LOC109029529 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC109029529 Gene

Orthologs for LOC109029529 Gene

No data available for Orthologs and Evolution for LOC109029529 Gene

Paralogs for LOC109029529 Gene

No data available for Paralogs for LOC109029529 Gene

Variants for LOC109029529 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC109029529 Gene

Disorders for LOC109029529 Gene

No disorders were found for LOC109029529 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC109029529 Gene

Publications for LOC109029529 Gene

  1. Angiotensin II triggers expression of the adrenal gland zona glomerulosa-specific 3β-hydroxysteroid dehydrogenase isoenzyme through de novo protein synthesis of the orphan nuclear receptors NGFIB and NURR1. (PMID: 25092869) Ota T … Okamura H (Molecular and cellular biology 2014) 3 54
  2. Gonadal transactivation of STARD1, CYP11A1 and HSD3B. (PMID: 22201776) King SR … LaVoie HA (Frontiers in bioscience (Landmark edition) 2012) 3 54
  3. Transcriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3B. (PMID: 19491374) Lavoie HA … King SR (Experimental biology and medicine (Maywood, N.J.) 2009) 3 54
  4. Identification of alpha-enolase as a nuclear DNA-binding protein in the zona fasciculata but not the zona reticularis of the human adrenal cortex. (PMID: 15642786) Wang W … Hornsby PJ (The Journal of endocrinology 2005) 3 54
  5. Molecular biology of the 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family. (PMID: 15632317) Simard J … Melner MH (Endocrine reviews 2005) 3 54

No data available for Mastermind for LOC109029529 Gene

Products for LOC109029529 Gene

Sources for LOC109029529 Gene