Aliases for LOC108868752 Gene
External Ids for LOC108868752 Gene
- Entrez Gene: 108868752
This region is known to undergo recombination with another region, the AZFc P1.1b recombination region, located about 7 Mb centromere-distal of this region. Recombination between these regions can result in a deletion of the large intervening sequence, and is known as a P4/distal-P1 deletion, causing azoospermia. Recombination is not thought to occur as a result of homologous recombination, since these regions do not share high sequence identity. This region is contained within a large palindromic region known as P4 (palindrome 4). AZFa, AZFb, and AZFc have been defined as regions on chromosome Yq11, each containing multiple genes. Deletions in any of these regions can cause spermatogenic defects. Recombination between this region and the AZFc P1.1b recombination region removes AZFb and part of the AZFc region. [provided by RefSeq, Oct 2016]
GeneCards Summary for LOC108868752 Gene
LOC108868752 (AZFb P4.1 Recombination Region) is a Biological Region gene. Diseases associated with LOC108868752 include Azoospermia.