Aliases for LOC108863624 Gene
External Ids for LOC108863624 Gene
- Entrez Gene: 108863624
This region is known to undergo non-allelic homologous recombination (NAHR) with another region, the AZFc P1.1 recombination region, located about 7.6 Mb centromere-distal of this region. NAHR between these regions can result in a deletion of the large intervening sequence, and is known as a P5/distal-P1 deletion, causing azoospermia. This region is contained within a very large palindromic region known as P5 (palindrome 5). AZFa, AZFb, and AZFc have been defined as regions on chromosome Yq11, each containing multiple genes. Deletions in any of these regions can cause spermatogenic defects. NAHR between this region and the AZFc P1.1 recombination region removes the AZFb and part of the AZFc region. This region contains an NAHR exchange region identified in multiple individuals, and also contains a meiotic recombination hotspot. Nearby NAHR regions and non-homologous recombination exchange regions have also been identified. [provided by RefSeq, Oct 2016]
GeneCards Summary for LOC108863624 Gene
LOC108863624 (AZFb P5.2 Recombination Region) is a Biological Region gene. Diseases associated with LOC108863624 include Azoospermia.