Aliases for LOC108281180 Gene
External Ids for LOC108281180 Gene
- Entrez Gene: 108281180
This region is found within an intron of the neurofibromin 1 (NF1) gene on the q arm of chromosome 17, and is known to undergo Alu-repeat-mediated non-allelic homologous recombination (NAHR), resulting in genomic rearrangements that can include deletions and duplications. Intronic numbering is based on NG_009018.1, which uses NM_001042492.2 as a reference standard. Genomic rearrangements as a result of NAHR can alter the NF1 coding region which can be a cause of neurofibromatosis, a tumor disorder characterized by cafe au lait spots, neurofibromas, and Lisch nodules. [provided by RefSeq, Jul 2016]
GeneCards Summary for LOC108281180 Gene
LOC108281180 (NF1 Intron 3 Alu-Mediated Recombination Region) is a Biological Region gene.