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Aliases for LOC108251791 Gene

Aliases for LOC108251791 Gene

  • FAM174B-LINC01578 Intergenic CAGE-Defined High Expression Enhancer 3
  • FAM174B-LINC01578 Interval High CAGE FANTOM5 Enhancer 3
  • Massively Parallel Reporter Assay Enhancer 236/237 3
  • ZFP161 Motif-Containing MPRA Enhancer 236/237 3
  • Sharpr-MPRA Regulatory Region 396 3

External Ids for LOC108251791 Gene

Summaries for LOC108251791 Gene

Entrez Gene Summary for LOC108251791 Gene

  • This genomic element is located in the intergenic region between the FAM174B (family with sequence similarity 174 member B) and LINC01578 (long intergenic non-protein coding RNA 1578) genes. It was defined as a high expression actively transcribed enhancer based on the presence of balanced bidirectional capped transcripts by cap analysis of gene expression (CAGE). It was validated as a functional enhancer by reporter assays in both HeLa and HepG2 cells. A sub-region was also validated as a functional enhancer by high-throughput massively parallel reporter assays (MPRAs) in HepG2 cells. This sub-region contains a conserved motif for the ZFP161 transcription factor, and mutation of the motif results in reduced enhancer activity. Another sub-region was further validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using MPRAs) in HepG2 cells (group: HepG2 Activating DNase unmatched - State 1:Tss, active promoter, TSS/CpG island region). [provided by RefSeq, Apr 2018]

GeneCards Summary for LOC108251791 Gene

LOC108251791 (FAM174B-LINC01578 Intergenic CAGE-Defined High Expression Enhancer) is a Biological Region gene.

Additional gene information for LOC108251791 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC108251791 Gene

Genomics for LOC108251791 Gene

Genomic Locations for LOC108251791 Gene

Genomic Locations for LOC108251791 Gene
chr15:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for LOC108251791 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for LOC108251791 Gene

No data available for GeneHancer (GH) Regulatory Elements for LOC108251791 Gene

Proteins for LOC108251791 Gene

Post-translational modifications for LOC108251791 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC108251791 Gene

Domains & Families for LOC108251791 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LOC108251791 Gene

Function for LOC108251791 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC108251791 Gene

Localization for LOC108251791 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC108251791 Gene

Pathways & Interactions for LOC108251791 Gene

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SuperPathways for LOC108251791 Gene

No Data Available

Interacting Proteins for LOC108251791 Gene

Gene Ontology (GO) - Biological Process for LOC108251791 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LOC108251791 Gene

Drugs & Compounds for LOC108251791 Gene

No Compound Related Data Available

Transcripts for LOC108251791 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LOC108251791 Gene

No ASD Table

No data available for mRNA/cDNA for LOC108251791 Gene

Expression for LOC108251791 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC108251791 Gene

Orthologs for LOC108251791 Gene

No data available for Orthologs and Evolution for LOC108251791 Gene

Paralogs for LOC108251791 Gene

No data available for Paralogs for LOC108251791 Gene

Variants for LOC108251791 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC108251791 Gene

Disorders for LOC108251791 Gene

No disorders were found for LOC108251791 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC108251791 Gene

Publications for LOC108251791 Gene

  1. Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions. (PMID: 27701403) Ernst J … Kellis M (Nature biotechnology 2016) 3 58
  2. An atlas of active enhancers across human cell types and tissues. (PMID: 24670763) Andersson R … Sandelin A (Nature 2014) 3 58
  3. Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay. (PMID: 23512712) Kheradpour P … Kellis M (Genome research 2013) 3 58
  4. Mapping and analysis of chromatin state dynamics in nine human cell types. (PMID: 21441907) Ernst J … Bernstein BE (Nature 2011) 3 58

No data available for External Links for LOC108251791 Gene

Products for LOC108251791 Gene

Sources for LOC108251791 Gene

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