Aliases for LOC105372273 Gene

Data sources for LOC105372273 Gene:

Subcategory (RNA class) for LOC105372273 Gene

lncRNA

Aliases for LOC105372273 Gene

External Ids for LOC105372273 Gene

Previous GeneCards Identifiers for LOC105372273 Gene

  • GC19U902142

Summaries for LOC105372273 Gene

GeneCards Summary for LOC105372273 Gene

LOC105372273 (Uncharacterized LOC105372273) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with LOC105372273 include Adams-Oliver Syndrome 2 and Oliver Syndrome.

Additional gene information for LOC105372273 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LOC105372273 Gene

Genomics for LOC105372273 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for LOC105372273 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J011202 Promoter/Enhancer 1.5 Ensembl ENCODE CraniofacialAtlas dbSUPER 255.7 +1.1 1065 3.1 ZBTB10 MNT CTCF ZIC2 ZNF395 REST MAX VEZF1 EBF1 SMC3 LOC105372273 ANGPTL8 DOCK6 KANK2 ENSG00000279807 HSALNG0124002
GH19J011200 Enhancer 0.3 dbSUPER 255.9 -1.4 -1395 1.2 GLIS2 LOC105372273 KANK2 ANGPTL8 DOCK6
GH19J011192 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 5.6 -6.4 -6401 7.1 ZBTB10 SMAD5 ZFP64 BHLHE40 ELF1 ZIC2 ZNF610 ZNF513 SIN3A ZNF395 KANK2 AB372777-008 HSALNG0124000 lnc-DOCK6-1 ANGPTL8 LOC105372273 ENSG00000267174 piR-52079-094 SPC24 DOCK6
GH19J011172 Enhancer 0.3 dbSUPER 5.3 -29.0 -29013 3.2 ARHGAP35 KANK2 LOC105372273 DOCK6 HSALNG0123998 piR-52079-094 SPC24
GH19J011209 Enhancer 0.7 dbSUPER 0.4 +7.5 7478 1.5 ZBTB10 ZEB1 ZNF639 ZEB2 BCL11B ZNF571 ZSCAN5A ZBTB48 SCRT1 ZNF530 ENSG00000279807 HSALNG0124002 lnc-KANK2-1 ILF3 ZNF627 ZNF441 ZNF625 ZNF136 ZNF844 ENSG00000242615
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LOC105372273 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for LOC105372273 Gene

Latest Assembly
chr19:11,202,645-11,216,168
(GRCh38/hg38)
Size:
13,524 bases
Orientation:
Plus strand

Previous Assembly
chr19:11,314,304-11,326,844
(GRCh37/hg19 by Entrez Gene)
Size:
12,541 bases
Orientation:
Plus strand

chr19:11,314,304-11,326,844
(GRCh37/hg19 by Ensembl)
Size:
12,541 bases
Orientation:
Plus strand

Genomic View for LOC105372273 Gene

Genes around LOC105372273 on UCSC Golden Path with GeneCards custom track
LOC105372273 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
LOC105372273 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LOC105372273 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LOC105372273 Gene

Proteins for LOC105372273 Gene

Post-translational modifications for LOC105372273 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC105372273 Gene

Domains & Families for LOC105372273 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LOC105372273 Gene

Function for LOC105372273 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC105372273 Gene

Localization for LOC105372273 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC105372273 Gene

Pathways & Interactions for LOC105372273 Gene

PathCards logo

SuperPathways for LOC105372273 Gene

No Data Available

Gene Ontology (GO) - Biological Process for LOC105372273 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LOC105372273 Gene

Drugs & Compounds for LOC105372273 Gene

No Compound Related Data Available

Transcripts for LOC105372273 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for LOC105372273 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000021CCD9_9606 lncRNA 572 5

RefSeq: NR_134909,

Ensembl: ENST00000588634 (view in UCSC) ,

LncBook: HSALNT0255780,

LNCipedia: lnc-ANGPTL8-1:1,

NONCODE: NONHSAT061122.2,

URS0000D5DCDB_9606 lncRNA 446 2

LncBook: HSALNT0255781,

LNCipedia: lnc-ANGPTL8-1:2,

URS0001BDDDA5_9606 lncRNA 3111 1

LncBook: HSALNT0255778,

URS00009B6523_9606 lncRNA 742 1

NONCODE: NONHSAT179452.1,

URS0001BCEA06_9606 lncRNA 569 1

LncBook: HSALNT0255780,

LOC105372273 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for LOC105372273 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for LOC105372273 Gene

No ASD Table

Relevant External Links for LOC105372273 Gene

GeneLoc Exon Structure for
LOC105372273

Expression for LOC105372273 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC105372273 Gene

Orthologs for LOC105372273 Gene

Evolution for LOC105372273 Gene

ENSEMBL:
Gene Tree for LOC105372273 (if available)
TreeFam:
Gene Tree for LOC105372273 (if available)

No data available for Orthologs for LOC105372273 Gene

Paralogs for LOC105372273 Gene

No data available for Paralogs for LOC105372273 Gene

Variants for LOC105372273 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LOC105372273 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
975215 Likely Benign: Intellectual disability 11,211,856(+) G/T
NM_020812.4(DOCK6):c.4671C>A (p.Asn1557Lys)
MISSENSE
975221 Likely Benign: Intellectual disability 11,204,204(+) T/A
NM_020812.4(DOCK6):c.5216A>T (p.His1739Leu)
MISSENSE
975685 Likely Benign: Intellectual disability 11,215,432(+) C/T
NM_020812.4(DOCK6):c.4061G>A (p.Arg1354Gln)
MISSENSE
rs112911897 Benign/Likely Benign: not provided 11,215,909(+) G/A
NM_020812.4(DOCK6):c.3913C>T (p.Arg1305Cys)
MISSENSE
rs117328686 Benign: Adams-Oliver syndrome 2 11,208,960(+) G/A
NM_020812.4(DOCK6):c.4895C>T (p.Ala1632Val)
MISSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for LOC105372273 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC105372273 Gene

Disorders for LOC105372273 Gene

MalaCards: The human disease database

(3) MalaCards diseases for LOC105372273 Gene - From: GCD

Disorder Aliases PubMed IDs
adams-oliver syndrome 2
  • aos2
oliver syndrome
  • postaxial polydactyly and mental retardation
adams-oliver syndrome
  • adams oliver syndrome
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for LOC105372273

Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with LOC105372273: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LOC105372273 Gene

Publications for LOC105372273 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3

No data available for Mastermind for LOC105372273 Gene

Products for LOC105372273 Gene

Sources for LOC105372273 Gene