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Aliases for LOC102724770 Gene

Aliases for LOC102724770 Gene

  • Protein DGCR6 3 5
  • DiGeorge Syndrome Critical Region 6 Isoform D 13
  • DiGeorge Syndrome Critical Region 6 3
  • AC007325.4 5

External Ids for LOC102724770 Gene

Previous GeneCards Identifiers for LOC102724770 Gene

  • GC22U901004
  • GC22P000131

Summaries for LOC102724770 Gene

GeneCards Summary for LOC102724770 Gene

LOC102724770 (Protein DGCR6) is a Protein Coding gene. Diseases associated with LOC102724770 include Digeorge Syndrome. An important paralog of this gene is DGCR6.

Additional gene information for LOC102724770 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC102724770 Gene

Genomics for LOC102724770 Gene

Genomic Locations for LOC102724770 Gene

Genomic Locations for LOC102724770 Gene
chr22:131,552-137,393
(GRCh38/hg38)
Size:
5,842 bases
Orientation:
Plus strand

Genomic View for LOC102724770 Gene

Genes around LOC102724770 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for LOC102724770 Gene

No data available for GeneHancer (GH) Regulatory Elements for LOC102724770 Gene

Proteins for LOC102724770 Gene

  • Protein details for LOC102724770 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    X5D7D2-X5D7D2_HUMAN
    Recommended name:
    DiGeorge syndrome critical region 6 isoform D
    Protein Accession:
    X5D7D2

    Protein attributes for LOC102724770 Gene

    Size:
    220 amino acids
    Molecular mass:
    24989 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LOC102724770 Gene

Post-translational modifications for LOC102724770 Gene

No Post-translational modifications

Other Protein References for LOC102724770 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LOC102724770 Gene

Domains & Families for LOC102724770 Gene

Gene Families for LOC102724770 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for LOC102724770 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LOC102724770: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LOC102724770 Gene

Function for LOC102724770 Gene

Gene Ontology (GO) - Molecular Function for LOC102724770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with LOC102724770: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC102724770 Gene

Localization for LOC102724770 Gene

Gene Ontology (GO) - Cellular Components for LOC102724770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0031012 extracellular matrix TAS 8733130
genes like me logo Genes that share ontologies with LOC102724770: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for LOC102724770 Gene

Pathways & Interactions for LOC102724770 Gene

PathCards logo

SuperPathways for LOC102724770 Gene

No Data Available

Interacting Proteins for LOC102724770 Gene

Gene Ontology (GO) - Biological Process for LOC102724770 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007155 cell adhesion TAS 8733130
GO:0009887 animal organ morphogenesis TAS 8733130
genes like me logo Genes that share ontologies with LOC102724770: view

No data available for Pathways by source and SIGNOR curated interactions for LOC102724770 Gene

Drugs & Compounds for LOC102724770 Gene

No Compound Related Data Available

Transcripts for LOC102724770 Gene

mRNA/cDNA for LOC102724770 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for LOC102724770 Gene

No ASD Table

Relevant External Links for LOC102724770 Gene

GeneLoc Exon Structure for
LOC102724770

Expression for LOC102724770 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC102724770 Gene

Orthologs for LOC102724770 Gene

This gene was present in the common ancestor of chordates.

Orthologs for LOC102724770 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia DGCR6 34
  • 92.26 (n)
dog
(Canis familiaris)
Mammalia DGCR6 34
  • 89.9 (n)
chicken
(Gallus gallus)
Aves DGCR6 34
  • 78.74 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia dgcr6 34
  • 65.81 (n)
zebrafish
(Danio rerio)
Actinopterygii dgcr6 34
  • 67.53 (n)
Species where no ortholog for LOC102724770 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LOC102724770 Gene

ENSEMBL:
Gene Tree for LOC102724770 (if available)
TreeFam:
Gene Tree for LOC102724770 (if available)

Paralogs for LOC102724770 Gene

Paralogs for LOC102724770 Gene

genes like me logo Genes that share paralogs with LOC102724770: view

Variants for LOC102724770 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC102724770 Gene

Disorders for LOC102724770 Gene

MalaCards: The human disease database

(1) MalaCards diseases for LOC102724770 Gene - From: GeneCards

Disorder Aliases PubMed IDs
digeorge syndrome
  • cayler cardiofacial syndrome
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with LOC102724770: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for LOC102724770 Gene

Publications for LOC102724770 Gene

  1. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. (PMID: 24722188) Corominas R … Iakoucheva LM (Nature communications 2014) 13 58
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  4. Two functional copies of the DGCR6 gene are present on human chromosome 22q11 due to a duplication of an ancestral locus. (PMID: 11157784) Edelmann L … Lupski J (Genome research 2001) 3 58
  5. Isolation of a novel gene from the DiGeorge syndrome critical region with homology to Drosophila gdl and to human LAMC1 genes. (PMID: 8733130) Demczuk S … Aurias A (Human molecular genetics 1996) 3 58

No data available for External Links for LOC102724770 Gene

Products for LOC102724770 Gene

Sources for LOC102724770 Gene

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