Aliases for LMOD1 Gene
External Ids for LMOD1 Gene
Previous GeneCards Identifiers for LMOD1 Gene
The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. [provided by RefSeq, Jul 2008]
GeneCards Summary for LMOD1 Gene
LMOD1 (Leiomodin 1) is a Protein Coding gene. Diseases associated with LMOD1 include Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome and Visceral Myopathy. Among its related pathways are Cardiac conduction and Smooth Muscle Contraction. Gene Ontology (GO) annotations related to this gene include actin binding and tropomyosin binding. An important paralog of this gene is LMOD2.
UniProtKB/Swiss-Prot Summary for LMOD1 Gene
Mediates nucleation of actin filaments.