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Aliases for LMO7DN Gene

Aliases for LMO7DN Gene

  • LMO7 Downstream Neighbor 2 3 5
  • C13orf45 3 4
  • Chromosome 13 Open Reading Frame 45 2
  • LMO7 Downstream Neighbor Protein 3

External Ids for LMO7DN Gene

Previous HGNC Symbols for LMO7DN Gene

  • C13orf45

Previous GeneCards Identifiers for LMO7DN Gene

  • GC13P076453

Summaries for LMO7DN Gene

GeneCards Summary for LMO7DN Gene

LMO7DN (LMO7 Downstream Neighbor) is a Protein Coding gene.

Additional gene information for LMO7DN Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LMO7DN Gene

Genomics for LMO7DN Gene

GeneHancer (GH) Regulatory Elements for LMO7DN Gene

Promoters and enhancers for LMO7DN Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13I075869 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 579.9 +0.4 384 2 CTCF ZNF654 L3MBTL2 TRIM22 ZNF384 REST RAD21 NR2F2 SMC3 ZNF143 LMO7DN LMO7-AS1 LMO7DN-IT1
GH13I075758 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 16.8 -108.8 -108798 5.8 PKNOX1 FOXA2 SMAD1 MLX ZFP64 ARID4B SIN3A DMAP1 IRF4 ETS1 LMO7 LMO7DN LMO7-AS1 COMMD6 GC13M075699 GC13M075860 ENSG00000261553
GH13I075796 Enhancer 0.8 ENCODE dbSUPER 19 -72.2 -72226 3.7 PKNOX1 FOXA2 NR2F1 HLF JUNB MAX DPF2 BATF RAD21 JUND LMO7DN LMO7-AS1 GC13M075860 GC13M075699 LMO7 ENSG00000261553
GH13I075715 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 10.1 -153.9 -153946 2.8 SMAD1 NFIB KLF17 FEZF1 RAD21 BRCA1 RFX5 GTF3C2 POLR3A ATF7 LMO7DN LMO7 GC13M075699 GC13M075860 ENSG00000261553
GH13I075791 Enhancer 1.2 Ensembl ENCODE dbSUPER 10.6 -77.4 -77411 3.6 ELF3 FOXA2 MLX ARID4B DMAP1 RAD21 RARA YY1 MIXL1 RXRA LMO7DN LMO7-AS1 GC13M075860 GC13M075699 LMO7 ENSG00000261553
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around LMO7DN on UCSC Golden Path with GeneCards custom track

Genomic Locations for LMO7DN Gene

Genomic Locations for LMO7DN Gene
chr13:75,870,571-75,883,812
(GRCh38/hg38)
Size:
13,242 bases
Orientation:
Plus strand
chr13:76,445,174-76,457,948
(GRCh37/hg19)

Genomic View for LMO7DN Gene

Genes around LMO7DN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LMO7DN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LMO7DN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LMO7DN Gene

Proteins for LMO7DN Gene

  • Protein details for LMO7DN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F2Z398-LMO7D_HUMAN
    Recommended name:
    LMO7 downstream neighbor protein
    Protein Accession:
    F2Z398
    Secondary Accessions:
    • Q8NAG9

    Protein attributes for LMO7DN Gene

    Size:
    122 amino acids
    Molecular mass:
    13273 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LMO7DN Gene

Post-translational modifications for LMO7DN Gene

No Post-translational modifications

Other Protein References for LMO7DN Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LMO7DN Gene

Domains & Families for LMO7DN Gene

Gene Families for LMO7DN Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for LMO7DN Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LMO7DN: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LMO7DN Gene

Function for LMO7DN Gene

Phenotypes From GWAS Catalog for LMO7DN Gene

Phenotypes for LMO7DN Gene

GenomeRNAi human phenotypes for LMO7DN:
genes like me logo Genes that share phenotypes with LMO7DN: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LMO7DN Gene

Localization for LMO7DN Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LMO7DN gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LMO7DN Gene

Pathways & Interactions for LMO7DN Gene

SuperPathways for LMO7DN Gene

No Data Available

Interacting Proteins for LMO7DN Gene

Gene Ontology (GO) - Biological Process for LMO7DN Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LMO7DN Gene

Drugs & Compounds for LMO7DN Gene

No Compound Related Data Available

Transcripts for LMO7DN Gene

mRNA/cDNA for LMO7DN Gene

(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for LMO7DN Gene

No ASD Table

Relevant External Links for LMO7DN Gene

GeneLoc Exon Structure for
LMO7DN
ECgene alternative splicing isoforms for
LMO7DN

Expression for LMO7DN Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LMO7DN Gene

mRNA differential expression in normal tissues according to GTEx for LMO7DN Gene

This gene is overexpressed in Nerve - Tibial (x23.6).

NURSA nuclear receptor signaling pathways regulating expression of LMO7DN Gene:

LMO7DN
genes like me logo Genes that share expression patterns with LMO7DN: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LMO7DN Gene

Orthologs for LMO7DN Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LMO7DN Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC736687 33
  • 98.63 (n)
C13orf45 34
  • 96 (a)
OneToOne
Species where no ortholog for LMO7DN was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LMO7DN Gene

ENSEMBL:
Gene Tree for LMO7DN (if available)
TreeFam:
Gene Tree for LMO7DN (if available)

Paralogs for LMO7DN Gene

No data available for Paralogs for LMO7DN Gene

Variants for LMO7DN Gene

Sequence variations from dbSNP and Humsavar for LMO7DN Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1000318782 -- 75,879,534(+) A/G intron_variant
rs1000710708 -- 75,872,586(+) G/A intron_variant
rs1000740200 -- 75,872,849(+) A/G intron_variant
rs1000946472 -- 75,868,322(+) A/G upstream_transcript_variant
rs1000984245 -- 75,878,917(+) G/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for LMO7DN Gene

Variant ID Type Subtype PubMed ID
esv2759950 CNV loss 17122850
nsv832646 CNV gain 17160897
nsv832649 CNV loss 17160897

Variation tolerance for LMO7DN Gene

Gene Damage Index Score: 1.16; 23.40% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LMO7DN Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LMO7DN

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LMO7DN Gene

Disorders for LMO7DN Gene

Additional Disease Information for LMO7DN

No disorders were found for LMO7DN Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LMO7DN Gene

Publications for LMO7DN Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 58

Products for LMO7DN Gene

Sources for LMO7DN Gene

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