Aliases for LMO1 Gene
External Ids for LMO1 Gene
Previous HGNC Symbols for LMO1 Gene
Previous GeneCards Identifiers for LMO1 Gene
This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012]
GeneCards Summary for LMO1 Gene
UniProtKB/Swiss-Prot Summary for LMO1 Gene
May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.