Aliases for LIPG Gene
External Ids for LIPG Gene
Previous GeneCards Identifiers for LIPG Gene
The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008]
GeneCards Summary for LIPG Gene
LIPG (Lipase G, Endothelial Type) is a Protein Coding gene. Diseases associated with LIPG include Gastric Leiomyoma and Body Mass Index Quantitative Trait Locus 11. Among its related pathways are Glycerolipid metabolism and Lipoprotein metabolism. Gene Ontology (GO) annotations related to this gene include heparin binding and phospholipase activity. An important paralog of this gene is LPL.
UniProtKB/Swiss-Prot for LIPG Gene
Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin.
Lipases are esterase enzymes that catalyze the hydrolysis of ester bonds within hydrophobic lipids. The diverse class of lipase enzymes includes diacylglycerol lipase (DAGL) and lipoprotein lipase (LPL) and endothelial lipase (LIPG).