Aliases for LINP1 Gene

Data sources for LINP1 Gene:

RNA type for LINP1 Gene

lncRNA

Aliases for LINP1 Gene

External Ids for LINP1 Gene

Previous GeneCards Identifiers for LINP1 Gene

  • GC10U902568

Summaries for LINP1 Gene

GeneCards Summary for LINP1 Gene

LINP1 (LncRNA In Non-Homologous End Joining Pathway 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with LINP1 include Cervical Cancer and Breast Cancer.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LINP1 Gene

Genomics for LINP1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for LINP1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J006736 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 257.4 +30.7 30673 7.6 JUND MAX EP300 FOXA2 ZNF623 RFX5 RARA ZNF433 TBP USF2 LINP1 piR-57133-033 NRBF2P5 ANKRD16 ENSG00000232807 FBH1 ENSG00000226647 RBM17 ENSG00000285988 HSALNG0075979
GH10J006711 Enhancer 0.4 Ensembl 250.7 +2.0 1971 0.2 ATF4 RFX1 POLR2A BMI1 LINP1 HSALNG0075975 ENSG00000285743 LOC107984203 PRKCQ
GH10J006709 Enhancer 0.2 Ensembl 250.7 0.0 -29 0.2 LINP1 HSALNG0075971 ENSG00000285743 LOC107984203 PRKCQ
GH10J006381 Enhancer 0.9 FANTOM5 Ensembl ENCODE 5.8 -325.2 -325230 6.6 CEBPB RFX5 EBF1 JUND TRIM28 HLF TCF12 EP300 ZKSCAN1 lnc-PFKFB3-12 PFKFB3 LINC02649 ENSG00000213994 IL15RA ENSG00000232807 FBH1 LINP1 HSALNG0075952 PRKCQ
GH10J006728 Enhancer 0.8 Ensembl ENCODE dbSUPER 6 +20.3 20271 2.4 CEBPB NFE2 BHLHE40 NFE2L2 MAFK HSALNG0075975 LINP1 ENSG00000285743 LOC107984203 PRKCQ
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINP1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for LINP1 Gene

Latest Assembly
chr10:6,709,530-6,740,532
(GRCh38/hg38)
Size:
31,003 bases
Orientation:
Plus strand

Previous Assembly
chr10:6,779,344-6,780,901
(GRCh37/hg19 by Entrez Gene)
Size:
1,558 bases
Orientation:
Plus strand

chr10:6,779,344-6,780,988
(GRCh37/hg19 by Ensembl)
Size:
1,645 bases
Orientation:
Plus strand

Genomic View for LINP1 Gene

Genes around LINP1 on UCSC Golden Path with GeneCards custom track
LINP1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
LINP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINP1 Gene

Proteins for LINP1 Gene

Post-translational modifications for LINP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINP1 Gene

Domains & Families for LINP1 Gene

Gene Families for LINP1 Gene

genes like me logo Genes that share domains with LINP1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LINP1 Gene

Function for LINP1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINP1 Gene

Localization for LINP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINP1 Gene

Pathways & Interactions for LINP1 Gene

PathCards logo

SuperPathways for LINP1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for LINP1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LINP1 Gene

Drugs & Compounds for LINP1 Gene

No Compound Related Data Available

Transcripts for LINP1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for LINP1 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS0000DBA980_9606 lncRNA 2529 1

Ensembl: ENST00000650334 (view in UCSC) ,

URS0000DBA7CA_9606 lncRNA 2096 1

Ensembl: ENST00000649087 (view in UCSC) ,

URS0000DB9900_9606 lncRNA 1290 1

Ensembl: ENST00000649511 (view in UCSC) ,

URS0000DB6E09_9606 lncRNA 1243 1

Ensembl: ENST00000417112 (view in UCSC) ,

URS0000A76D17_9606 lncRNA 830 1

RefSeq: NR_138480,

LINP1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for LINP1 Gene

2 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for LINP1 Gene

No ASD Table

Relevant External Links for LINP1 Gene

GeneLoc Exon Structure for
LINP1

Expression for LINP1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINP1 Gene

Orthologs for LINP1 Gene

Evolution for LINP1 Gene

ENSEMBL:
Gene Tree for LINP1 (if available)
TreeFam:
Gene Tree for LINP1 (if available)
Alliance of Genome Resources:
Additional Orthologs for LINP1

No data available for Orthologs for LINP1 Gene

Paralogs for LINP1 Gene

No data available for Paralogs for LINP1 Gene

Variants for LINP1 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for LINP1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Additional Variant Information for LINP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINP1
Leiden Open Variation Database (LOVD)
LINP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for LINP1 Gene

Disorders for LINP1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for LINP1 Gene - From: LNC and GCD

Disorder Aliases PubMed IDs
cervical cancer
  • cervical cancer, somatic
breast cancer
  • breast cancer, familial
- elite association - COSMIC cancer census association via MalaCards
Search LINP1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for LINP1

genes like me logo Genes that share disorders with LINP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINP1 Gene

Publications for LINP1 Gene

  1. Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer. (PMID: 27111890) Zhang Y … Zhang L (Nature structural & molecular biology 2016) 2 3 72
  2. Mechanism of efficient double-strand break repair by a long non-coding RNA. (PMID: 33045735) Thapar R … Tainer JA (Nucleic acids research 2020) 2 3
  3. LINP1 facilitates DNA damage repair through non-homologous end joining (NHEJ) pathway and subsequently decreases the sensitivity of cervical cancer cells to ionizing radiation. (PMID: 29527968) Wang X … Sun X (Cell cycle (Georgetown, Tex.) 2018) 3 72
  4. Long noncoding RNA LINP1 acts as an oncogene and promotes chemoresistance in breast cancer. (PMID: 29293402) Liang Y … Yang Q (Cancer biology & therapy 2018) 3 72
  5. LncRNA-AK149641 regulates the secretion of tumor necrosis factor-α in P815 mast cells by targeting the nuclear factor-kappa B signaling pathway. (PMID: 33024135) Zhou Y … Liu F (Scientific reports 2020) 3

Products for LINP1 Gene

Sources for LINP1 Gene