Aliases for LINC02694 Gene

RNA type for LINC02694 Gene

lncRNA

Aliases for LINC02694 Gene

External Ids for LINC02694 Gene

Previous HGNC Symbols for LINC02694 Gene

  • C15orf53

Previous GeneCards Identifiers for LINC02694 Gene

  • GC15P038697
  • GC15P038630
  • GC15P038616

Summaries for LINC02694 Gene

GeneCards Summary for LINC02694 Gene

LINC02694 (Long Intergenic Non-Protein Coding RNA 2694) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with LINC02694 include Schizophrenia 10 and Spastic Paraplegia 11, Autosomal Recessive.

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LINC02694 Gene

Genomics for LINC02694 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for LINC02694 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC02694 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for LINC02694

Genomic Locations for LINC02694 Gene

Latest Assembly
chr15:38,609,803-39,180,499
(GRCh38/hg38)
Size:
570,697 bases
Orientation:
Plus strand

Previous Assembly
chr15:38,988,799-38,992,239
(GRCh37/hg19 by Entrez Gene)
Size:
3,441 bases
Orientation:
Plus strand

chr15:38,988,799-38,992,239
(GRCh37/hg19 by Ensembl)
Size:
3,441 bases
Orientation:
Plus strand

Genomic View for LINC02694 Gene

Genes around LINC02694 on UCSC Golden Path with GeneCards custom track
LINC02694 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
LINC02694 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC02694 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC02694 Gene

Proteins for LINC02694 Gene

  • Protein details for LINC02694 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NAA6-CO053_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by LINC02694
    Protein Accession:
    Q8NAA6

    Protein attributes for LINC02694 Gene

    Size:
    179 amino acids
    Molecular mass:
    19737 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LINC02694 Gene

Post-translational modifications for LINC02694 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for LINC02694 Gene

Domains & Families for LINC02694 Gene

Gene Families for LINC02694 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for LINC02694 Gene

InterPro:
genes like me logo Genes that share domains with LINC02694: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LINC02694 Gene

Function for LINC02694 Gene

Phenotypes From GWAS Catalog for LINC02694 Gene

genes like me logo Genes that share phenotypes with LINC02694: view

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC02694 Gene

Localization for LINC02694 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC02694 gene
Compartment Confidence
extracellular 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC02694 Gene

Pathways & Interactions for LINC02694 Gene

PathCards logo

SuperPathways for LINC02694 Gene

No Data Available

Gene Ontology (GO) - Biological Process for LINC02694 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LINC02694 Gene

Drugs & Compounds for LINC02694 Gene

No Compound Related Data Available

Transcripts for LINC02694 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for LINC02694 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000027B0E7_9606 lncRNA 509 4

Ensembl: ENST00000557946 (view in UCSC) ,

LncBook: HSALNT0218738,

LNCipedia: lnc-FAM98B-5:2,

NONCODE: NONHSAT041718.2,

URS00004827A5_9606 lncRNA 392 3

Ensembl: ENST00000560203 (view in UCSC) ,

LNCipedia: lnc-FAM98B-5:1,

NONCODE: NONHSAT041717.2,

URS0000D6130C_9606 lncRNA 2043 2

RefSeq: NR_160786,

Ensembl: ENST00000643127 (view in UCSC) ,

URS0000D5F860_9606 lncRNA 2032 1

Ensembl: ENST00000647456 (view in UCSC) ,

URS0000D61CD9_9606 lncRNA 1855 1

Ensembl: ENST00000644461 (view in UCSC) ,

LINC02694 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for LINC02694 Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :

CRISPR products for research

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LINC02694

Alternative Splicing Database (ASD) splice patterns (SP) for LINC02694 Gene

No ASD Table

Relevant External Links for LINC02694 Gene

GeneLoc Exon Structure for
LINC02694

Expression for LINC02694 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LINC02694

SOURCE GeneReport for Unigene cluster for LINC02694 Gene:

Hs.448785
No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC02694 Gene

Orthologs for LINC02694 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LINC02694 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C15orf53 30
  • 98 (a)
OneToOne
C15H15orf53 29
  • 97.95 (n)
Species where no ortholog for LINC02694 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for LINC02694 Gene

ENSEMBL:
Gene Tree for LINC02694 (if available)
TreeFam:
Gene Tree for LINC02694 (if available)
Alliance of Genome Resources:
Additional Orthologs for LINC02694

Paralogs for LINC02694 Gene

No data available for Paralogs for LINC02694 Gene

Variants for LINC02694 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LINC02694 Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
rs11857596 -- p.Ala39Val
rs7165988 -- p.Leu3Val

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for LINC02694 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for LINC02694 Gene

Variant ID Type Subtype PubMed ID
nsv1046994 CNV gain 25217958
nsv525770 CNV gain 19592680

Variation tolerance for LINC02694 Gene

Residual Variation Intolerance Score: 54.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.49; 55.25% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LINC02694 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC02694
Leiden Open Variation Database (LOVD)
LINC02694

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LINC02694 Gene

Disorders for LINC02694 Gene

MalaCards: The human disease database

(2) MalaCards diseases for LINC02694 Gene - From: COP

Disorder Aliases PubMed IDs
schizophrenia 10
  • sczd10
spastic paraplegia 11, autosomal recessive
  • spg11
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for LINC02694

genes like me logo Genes that share disorders with LINC02694: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC02694 Gene

Publications for LINC02694 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  2. A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. (PMID: 23089632) Wang JC … Goate AM (Molecular psychiatry 2013) 3
  3. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) Psychiatric GWAS Consortium Bipolar Disorder Working Group (Nature genetics 2011) 3
  4. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. (PMID: 20351715) Liu Y … Wellcome Trust Case-Control Consortium (Molecular psychiatry 2011) 3
  5. Genome-wide association study of bipolar disorder in European American and African American individuals. (PMID: 19488044) Smith EN … Kelsoe JR (Molecular psychiatry 2009) 3

No data available for Mastermind for LINC02694 Gene

Products for LINC02694 Gene

Sources for LINC02694 Gene