Aliases for LINC02694 Gene

Subcategory (RNA class) for LINC02694 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for LINC02694 Gene

  • Long Intergenic Non-Protein Coding RNA 2694 2 3 5
  • C15orf53 3 4
  • Putative Uncharacterized Protein Encoded By LINC02694 4
  • Chromosome 15 Open Reading Frame 53 2
  • Uncharacterized Protein C15orf53 3
  • NONHSAG016548 92
  • HSALNG0105127 167
  • Lnc-FAM98B-5 168
  • LINC02694 2

External Ids for LINC02694 Gene

Previous HGNC Symbols for LINC02694 Gene

  • C15orf53

Previous GeneCards Identifiers for LINC02694 Gene

  • GC15P038697

Summaries for LINC02694 Gene

GeneCards Summary for LINC02694 Gene

LINC02694 (Long Intergenic Non-Protein Coding RNA 2694) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with LINC02694 include Schizophrenia 10 and Spastic Paraplegia 11, Autosomal Recessive.

Additional gene information for LINC02694 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LINC02694 Gene

Genomics for LINC02694 Gene

GeneHancer (GH) Regulatory Elements for LINC02694 Gene

Promoters and enhancers for LINC02694 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J038626 Promoter/Enhancer 0.7 Ensembl dbSUPER 500.7 -1.3 -1304 0.2 IKZF2 PKNOX1 RELB LINC02694 RASGRP1 piR-32214-200
GH15J038628 Enhancer 0.6 ENCODE 500.7 -0.1 -123 0.1 CTCF REST MYC NCOR1 FOSL1 MNT FOXK2 MAFG GATA2 DPF2 LINC02694 piR-32214-200
GH15J038453 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE CraniofacialAtlas 10.9 -173.3 -173304 2.6 ZBTB40 ZNF217 ZSCAN5C SIN3A TCF12 POLR2G SP1 GTF2E2 PHF8 FOS FAM98B LINC02694 RASGRP1 piR-53522-002
GH15J038669 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 11.8 +43.5 43451 4.6 SIN3A EP300 KLF4 RELA RCOR1 TRIM22 NFYB POLR2A BCL11A CREB1 LOC105370775 RASGRP1 LINC02694 FAM98B
GH15J038531 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 10.6 -88.8 -88805 18.8 NRF1 JUND ZBTB11 REST MYC ATF2 TAF9B CTCF ZNF316 ZNF263 RASGRP1 LINC02694 FAM98B RF00019-050 ENSG00000259598
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC02694 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for LINC02694

Genomic Locations for LINC02694 Gene

Genomic Locations for LINC02694 Gene
chr15:38,628,005-39,180,499
(GRCh38/hg38)
Size:
552,495 bases
Orientation:
Plus strand
chr15:38,988,799-38,992,239
(GRCh37/hg19)
Size:
3,441 bases
Orientation:
Plus strand

Genomic View for LINC02694 Gene

Genes around LINC02694 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC02694 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC02694 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC02694 Gene

Proteins for LINC02694 Gene

  • Protein details for LINC02694 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NAA6-CO053_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by LINC02694
    Protein Accession:
    Q8NAA6

    Protein attributes for LINC02694 Gene

    Size:
    179 amino acids
    Molecular mass:
    19737 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LINC02694 Gene

Post-translational modifications for LINC02694 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for LINC02694 Gene

Domains & Families for LINC02694 Gene

Gene Families for LINC02694 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for LINC02694 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with LINC02694: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LINC02694 Gene

Function for LINC02694 Gene

Phenotypes From GWAS Catalog for LINC02694 Gene

genes like me logo Genes that share phenotypes with LINC02694: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC02694 Gene

Localization for LINC02694 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC02694 gene
Compartment Confidence
extracellular 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC02694 Gene

Pathways & Interactions for LINC02694 Gene

PathCards logo

SuperPathways for LINC02694 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for LINC02694 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LINC02694 Gene

Drugs & Compounds for LINC02694 Gene

No Compound Related Data Available

Transcripts for LINC02694 Gene

mRNA/cDNA for LINC02694 Gene

9 RNACentral transcripts :
2 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 NONCODE transcripts :
1 LncBook transcripts :
2 LNCipedia transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for LINC02694 Gene

No ASD Table

Relevant External Links for LINC02694 Gene

GeneLoc Exon Structure for
LINC02694

Expression for LINC02694 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LINC02694

SOURCE GeneReport for Unigene cluster for LINC02694 Gene:

Hs.448785
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC02694 Gene

Orthologs for LINC02694 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LINC02694 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C15orf53 31
  • 98 (a)
OneToOne
C15H15orf53 30
  • 97.95 (n)
Species where no ortholog for LINC02694 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LINC02694 Gene

ENSEMBL:
Gene Tree for LINC02694 (if available)
TreeFam:
Gene Tree for LINC02694 (if available)

Paralogs for LINC02694 Gene

No data available for Paralogs for LINC02694 Gene

Variants for LINC02694 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LINC02694 Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
rs11857596 - p.Ala39Val
rs7165988 - p.Leu3Val

Structural Variations from Database of Genomic Variants (DGV) for LINC02694 Gene

Variant ID Type Subtype PubMed ID
nsv1046994 CNV gain 25217958
nsv525770 CNV gain 19592680

Variation tolerance for LINC02694 Gene

Residual Variation Intolerance Score: 54.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.49; 55.25% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LINC02694 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC02694

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Additional dbSNP identifiers (rs#s) for LINC02694 Gene

Disorders for LINC02694 Gene

MalaCards: The human disease database

(3) MalaCards diseases for LINC02694 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
schizophrenia 10
  • sczd10
spastic paraplegia 11, autosomal recessive
  • spg11
bipolar disorder
  • major affective disorder 1
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with LINC02694: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for LINC02694 Gene

Publications for LINC02694 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  2. A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. (PMID: 23089632) Wang JC … Goate AM (Molecular psychiatry 2013) 3 54
  3. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) Psychiatric GWAS Consortium Bipolar Disorder Working Group (Nature genetics 2011) 3 54
  4. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. (PMID: 20351715) Liu Y … Wellcome Trust Case-Control Consortium (Molecular psychiatry 2011) 3 54
  5. Genome-wide association study of bipolar disorder in European American and African American individuals. (PMID: 19488044) Smith EN … Kelsoe JR (Molecular psychiatry 2009) 3 54

No data available for Mastermind for LINC02694 Gene

Products for LINC02694 Gene

Sources for LINC02694 Gene