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Aliases for LINC01549 Gene

Subcategory (RNA class) for LINC01549 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for LINC01549 Gene

  • Long Intergenic Non-Protein Coding RNA 1549 2 3 5
  • C21orf37 3 4
  • Chromosome 21 Open Reading Frame 37 2

External Ids for LINC01549 Gene

Previous HGNC Symbols for LINC01549 Gene

  • C21orf37

Summaries for LINC01549 Gene

GeneCards Summary for LINC01549 Gene

LINC01549 (Long Intergenic Non-Protein Coding RNA 1549) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for LINC01549 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC01549 Gene

Genomics for LINC01549 Gene

GeneHancer (GH) Regulatory Elements for LINC01549 Gene

Promoters and enhancers for LINC01549 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J017438 Enhancer 0.7 ENCODE 650.7 -0.3 -336 1.6 SOX13 TFAP4 SAP130 ARID4B ZIC2 ZNF644 POLR2A PRPF4 CREM EZH2 LINC01549 RNU6-113P
GH21J017436 Enhancer 0.6 ENCODE 650.7 -1.9 -1882 0.2 SOX13 GATAD2A ZNF189 GFI1B ZNF10 OSR2 ZSCAN21 GATA3 ZSCAN5C PRDM4 LINC01549 RNU6-113P
GH21J017437 Enhancer 0.2 ENCODE 650.7 -1.5 -1490 0.1 LINC01549 RNU6-113P
GH21J017460 Enhancer 1.1 Ensembl ENCODE 12.2 +23.5 23536 3.6 FOXA2 ARID4B DMAP1 ZNF48 ETS1 YY1 FOS RXRA SP5 REST LINC01549 TRG-GCC1-5 RPL39P40
GH21J017465 Enhancer 1 Ensembl ENCODE 12.5 +28.3 28277 2.8 ELF3 SOX13 USF1 FOXA2 RARA ZNF121 PRDM10 CREM MIXL1 GATAD2A LINC01549 RNU6-113P TRG-GCC1-5 RPL39P40
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC01549 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC01549 Gene

Genomic Locations for LINC01549 Gene
chr21:17,438,890-17,449,185
(GRCh38/hg38)
Size:
10,296 bases
Orientation:
Plus strand
chr21:18,811,208-18,821,503
(GRCh37/hg19)
Size:
10,296 bases
Orientation:
Plus strand

Genomic View for LINC01549 Gene

Genes around LINC01549 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC01549 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC01549 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC01549 Gene

Proteins for LINC01549 Gene

  • Protein details for LINC01549 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NIU2-CU037_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by LINC01549
    Protein Accession:
    A6NIU2

    Protein attributes for LINC01549 Gene

    Size:
    74 amino acids
    Molecular mass:
    8470 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LINC01549 Gene

Post-translational modifications for LINC01549 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for LINC01549 Gene

Domains & Families for LINC01549 Gene

Protein Domains for LINC01549 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC01549: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC01549 Gene

Function for LINC01549 Gene

Phenotypes for LINC01549 Gene

genes like me logo Genes that share phenotypes with LINC01549: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC01549 Gene

Localization for LINC01549 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC01549 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC01549 Gene

Pathways & Interactions for LINC01549 Gene

SuperPathways for LINC01549 Gene

No Data Available

Interacting Proteins for LINC01549 Gene

Gene Ontology (GO) - Biological Process for LINC01549 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC01549 Gene

Drugs & Compounds for LINC01549 Gene

No Compound Related Data Available

Transcripts for LINC01549 Gene

mRNA/cDNA for LINC01549 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(4) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for LINC01549 Gene

No ASD Table

Relevant External Links for LINC01549 Gene

GeneLoc Exon Structure for
LINC01549
ECgene alternative splicing isoforms for
LINC01549

Expression for LINC01549 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC01549 Gene

NURSA nuclear receptor signaling pathways regulating expression of LINC01549 Gene:

LINC01549
genes like me logo Genes that share expression patterns with LINC01549: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC01549 Gene

Orthologs for LINC01549 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for LINC01549 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C21orf37 34
  • 99 (a)
OneToOne
Species where no ortholog for LINC01549 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for LINC01549 Gene

ENSEMBL:
Gene Tree for LINC01549 (if available)
TreeFam:
Gene Tree for LINC01549 (if available)

Paralogs for LINC01549 Gene

No data available for Paralogs for LINC01549 Gene

Variants for LINC01549 Gene

Sequence variations from dbSNP and Humsavar for LINC01549 Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1000116959 -- 17,444,881(+) C/T intron_variant
rs1000184625 -- 17,443,435(+) G/A intron_variant
rs1000268249 -- 17,438,774(+) T/A upstream_transcript_variant
rs1000540445 -- 17,439,572(+) T/C intron_variant
rs1000602429 -- 17,440,075(+) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for LINC01549 Gene

Variant ID Type Subtype PubMed ID
dgv4391n100 CNV gain 25217958
esv2723192 CNV deletion 23290073
esv3575381 CNV gain 25503493
esv3893382 CNV gain 25118596
nsv475950 CNV novel sequence insertion 20440878

Variation tolerance for LINC01549 Gene

Gene Damage Index Score: 0.46; 9.98% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LINC01549 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC01549

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LINC01549 Gene

Disorders for LINC01549 Gene

Additional Disease Information for LINC01549

No disorders were found for LINC01549 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LINC01549 Gene

Publications for LINC01549 Gene

  1. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M … Chromosome 21 mapping and sequencing consortium (Nature 2000) 3 4 58
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  3. The sequence of the human genome. (PMID: 11181995) Venter JC … Zhu X (Science (New York, N.Y.) 2001) 3 58

Products for LINC01549 Gene

Sources for LINC01549 Gene

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