Aliases for LINC00970 Gene

Subcategory (RNA class) for LINC00970 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for LINC00970 Gene

  • Long Intergenic Non-Protein Coding RNA 970 2 3 5
  • LINC00970 2 168
  • HSALNG0008302 167
  • NONHSAG003406 92

External Ids for LINC00970 Gene

Summaries for LINC00970 Gene

GeneCards Summary for LINC00970 Gene

LINC00970 (Long Intergenic Non-Protein Coding RNA 970) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with LINC00970 include Fuchs' Endothelial Dystrophy and Recurrent Corneal Erosion. Among its related pathways are LncRNA-mediated mechanisms of therapeutic resistance.

Additional gene information for LINC00970 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LINC00970 Gene

Genomics for LINC00970 Gene

GeneHancer (GH) Regulatory Elements for LINC00970 Gene

Promoters and enhancers for LINC00970 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J169086 Enhancer 1.1 Ensembl ENCODE dbSUPER 500.7 +0.0 4 2.8 EP300 ZSCAN5C NCOR1 TCF7 RFX1 SKI SMC3 GATA3 BMI1 SAP130 LINC00970 ENSG00000285622 RNA5SP66
GH01J169088 Enhancer 0.3 Ensembl dbSUPER 500.7 -2.0 -1996 0.4 LINC00970 ENSG00000285622
GH01J169101 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.7 -21.2 -21197 14 EP300 ZNF217 CTCF SIN3A NRF1 TCF12 POLR2G USF1 NCOR1 RBAK ATP1B1 SCYL3 C1orf112 RN7SL333P LINC00970 NME7 CCDC181 ENSG00000229757 XCL2 ENSG00000237707
GH01J169115 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.7 -29.6 -29642 2.6 EP300 FOXK2 SIN3A TCF12 NCOR1 KDM6A TCF7 RFX1 RELA ZBTB25 NME7 LINC00970 ENSG00000235575 ATP1B1 piR-57724
GH01J169124 Enhancer 0.9 Ensembl ENCODE dbSUPER 10.9 -37.6 -37619 0.8 RFX1 GATAD2B CTBP1 GATA3 PKNOX1 DPF2 POLR2A AGO2 RFX5 MNT NME7 LINC00970 ATP1B1 piR-57724
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC00970 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC00970 Gene

Genomic Locations for LINC00970 Gene
chr1:168,903,905-169,087,005
(GRCh38/hg38)
Size:
183,101 bases
Orientation:
Minus strand
chr1:168,873,143-169,056,243
(GRCh37/hg19)
Size:
183,101 bases
Orientation:
Minus strand

Genomic View for LINC00970 Gene

Genes around LINC00970 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC00970 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC00970 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC00970 Gene

Proteins for LINC00970 Gene

Post-translational modifications for LINC00970 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC00970 Gene

Domains & Families for LINC00970 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LINC00970 Gene

Function for LINC00970 Gene

Phenotypes From GWAS Catalog for LINC00970 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC00970 Gene

Localization for LINC00970 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC00970 Gene

Pathways & Interactions for LINC00970 Gene

PathCards logo

SuperPathways for LINC00970 Gene

genes like me logo Genes that share pathways with LINC00970: view

Pathways by source for LINC00970 Gene

1 BioSystems pathway for LINC00970 Gene
;

Gene Ontology (GO) - Biological Process for LINC00970 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for LINC00970 Gene

Drugs & Compounds for LINC00970 Gene

No Compound Related Data Available

Transcripts for LINC00970 Gene

mRNA/cDNA for LINC00970 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
1 NONCODE transcripts :
1 LncBook transcripts :
1 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for LINC00970 Gene

No ASD Table

Relevant External Links for LINC00970 Gene

GeneLoc Exon Structure for
LINC00970

Expression for LINC00970 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for LINC00970 Gene

mRNA differential expression in normal tissues according to GTEx for LINC00970 Gene

This gene is overexpressed in Minor Salivary Gland (x14.8), Brain - Hippocampus (x4.9), and Brain - Anterior cingulate cortex (BA24) (x4.1).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LINC00970

genes like me logo Genes that share expression patterns with LINC00970: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC00970 Gene

Orthologs for LINC00970 Gene

Evolution for LINC00970 Gene

ENSEMBL:
Gene Tree for LINC00970 (if available)
TreeFam:
Gene Tree for LINC00970 (if available)

No data available for Orthologs for LINC00970 Gene

Paralogs for LINC00970 Gene

No data available for Paralogs for LINC00970 Gene

Variants for LINC00970 Gene

Additional dbSNP identifiers (rs#s) for LINC00970 Gene

Structural Variations from Database of Genomic Variants (DGV) for LINC00970 Gene

Variant ID Type Subtype PubMed ID
dgv220n106 CNV deletion 24896259
dgv623n54 CNV loss 21841781
dgv624n54 CNV loss 21841781
dgv86n67 CNV gain 20364138
dgv87n67 CNV gain 20364138
esv1381365 CNV deletion 17803354
esv2147293 CNV deletion 18987734
esv22990 CNV gain 19812545
esv2678420 CNV deletion 23128226
esv2719262 CNV deletion 23290073
esv2719273 CNV deletion 23290073
esv2719284 CNV deletion 23290073
esv2719295 CNV deletion 23290073
esv2719306 CNV deletion 23290073
esv2719317 CNV deletion 23290073
esv2719328 CNV deletion 23290073
esv3000988 CNV deletion 24192839
esv33957 CNV loss 17666407
esv3542322 CNV deletion 23714750
esv3542333 CNV deletion 23714750
esv3578244 CNV loss 25503493
esv3587876 CNV loss 21293372
esv3587877 CNV loss 21293372
esv3587878 CNV loss 21293372
nsv1078878 OTHER inversion 25765185
nsv1135754 CNV deletion 24896259
nsv1145380 CNV deletion 24896259
nsv437258 CNV loss 16327808
nsv548146 CNV loss 21841781
nsv548152 CNV loss 21841781
nsv819267 CNV gain 19587683
nsv820513 CNV deletion 20802225
nsv825320 CNV loss 20364138
nsv831858 CNV gain 17160897
nsv957196 CNV deletion 24416366

Additional Variant Information for LINC00970 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC00970

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for LINC00970 Gene

Disorders for LINC00970 Gene

MalaCards: The human disease database

(2) MalaCards diseases for LINC00970 Gene - From: DISEASES

Disorder Aliases PubMed IDs
fuchs' endothelial dystrophy
  • fced
recurrent corneal erosion
  • recurrent erosion of cornea
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for LINC00970

genes like me logo Genes that share disorders with LINC00970: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC00970 Gene

Publications for LINC00970 Gene

  1. The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell. (PMID: 23741487) Yang Y … Wang J (PloS one 2013) 2 3 54
  2. A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels. (PMID: 25240745) López S … Soria JM (Mitochondrion 2014) 3 54
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54

Products for LINC00970 Gene

Sources for LINC00970 Gene