Aliases for LINC00668 Gene

Subcategory (RNA class) for LINC00668 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for LINC00668 Gene

  • Long Intergenic Non-Protein Coding RNA 668 2 3 5
  • LINC00668 2 5 165
  • NONHSAG023287.2 91
  • HSALNG0119819 164

External Ids for LINC00668 Gene

Previous GeneCards Identifiers for LINC00668 Gene

  • GC18M006947

Summaries for LINC00668 Gene

GeneCards Summary for LINC00668 Gene

LINC00668 (Long Intergenic Non-Protein Coding RNA 668) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with LINC00668 include Oral Squamous Cell Carcinoma and Gastric Cancer.

Additional gene information for LINC00668 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LINC00668 Gene

Genomics for LINC00668 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for LINC00668 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J006930 Promoter 0.9 EPDnew 600.7 +0.2 172 0.1 PKNOX1 HDAC1 GABPA NRF1 MGA POLR2A MTA3 E2F5 NFRKB NR2C2 LINC00668 piR-31339 piR-38260 piR-32090 piR-48974 LAMA1 ARHGAP28
GH18J006931 Promoter 0.9 EPDnew 600.7 0.0 -3 0.1 PKNOX1 NR2C1 HDAC1 GABPA NRF1 MTA3 E2F5 NFRKB NR2C2 MYC LINC00668 piR-31339 piR-38260 piR-32090 piR-48974 RF00026-463 LAMA1 ARHGAP28
GH18J006928 Promoter 0.3 EPDnew 605.3 +1.4 1429 0.1 LINC00668 SCML2P1 lnc-ARHGAP28-7 piR-31339 piR-38125-002 piR-38260 piR-32090 piR-48974 LAMA1 ARHGAP28
GH18J006926 Enhancer 0.6 ENCODE 10.8 +2.8 2768 1.4 SOX6 EP300 ZNF766 NR2C2 ZBTB11 GABPA ZNF589 ETV1 L3MBTL2 ZFX SCML2P1 lnc-ARHGAP28-7 piR-33103-009 piR-31339 piR-38125-002 piR-38260 piR-32090 piR-35132 piR-48974 piR-49687
GH18J006993 Enhancer 0.3 Ensembl ENCODE 6.3 -64.7 -64702 2.2 LINC00668 lnc-L3MBTL4-4 hsa-miR-5095-237 LAMA1 ARHGAP28
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC00668 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for LINC00668 Gene

Genomic Locations for LINC00668 Gene
chr18:6,919,496-6,929,996
(GRCh38/hg38)
Size:
10,501 bases
Orientation:
Minus strand
chr18:6,919,495-6,929,965
(GRCh37/hg19)
Size:
10,471 bases
Orientation:
Minus strand

Genomic View for LINC00668 Gene

Genes around LINC00668 on UCSC Golden Path with GeneCards custom track
LINC00668 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
LINC00668 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC00668 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC00668 Gene

Proteins for LINC00668 Gene

Post-translational modifications for LINC00668 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC00668 Gene

Domains & Families for LINC00668 Gene

Gene Families for LINC00668 Gene

genes like me logo Genes that share domains with LINC00668: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LINC00668 Gene

Function for LINC00668 Gene

Phenotypes for LINC00668 Gene

genes like me logo Genes that share phenotypes with LINC00668: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC00668 Gene

Localization for LINC00668 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC00668 gene
Compartment Confidence
extracellular 1
cytoskeleton 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC00668 Gene

Pathways & Interactions for LINC00668 Gene

PathCards logo

SuperPathways for LINC00668 Gene

No Data Available

Gene Ontology (GO) - Biological Process for LINC00668 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LINC00668 Gene

Drugs & Compounds for LINC00668 Gene

No Compound Related Data Available

Transcripts for LINC00668 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for LINC00668 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E986_9606 lncRNA 1751 5

HGNC: 44328,

RefSeq: NR_034100,

LncBook: HSALNT0247515,

LNCipedia: LINC00668:7,

NONCODE: NONHSAT057125.2,

URS000046DA63_9606 lncRNA 1902 4

Ensembl: ENST00000581725 (view in UCSC) ,

LncBook: HSALNT0247502,

LNCipedia: LINC00668:9,

NONCODE: NONHSAT057124.2,

URS000007CA50_9606 lncRNA 695 4

Ensembl: ENST00000578278 (view in UCSC) ,

LncBook: HSALNT0247516,

LNCipedia: LINC00668:14,

NONCODE: NONHSAT057126.2,

URS00004B17DF_9606 lncRNA 605 4

Ensembl: ENST00000579012 (view in UCSC) ,

LncBook: HSALNT0247532,

LNCipedia: LINC00668:1,

NONCODE: NONHSAT057143.2,

URS0000161674_9606 lncRNA 582 4

Ensembl: ENST00000583316 (view in UCSC) ,

LncBook: HSALNT0247528,

LNCipedia: LINC00668:10,

NONCODE: NONHSAT057134.2,

LINC00668 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for LINC00668 Gene

1 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for LINC00668 Gene

No ASD Table

Relevant External Links for LINC00668 Gene

GeneLoc Exon Structure for
LINC00668

Expression for LINC00668 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for LINC00668 Gene

mRNA differential expression in normal tissues according to GTEx for LINC00668 Gene

This gene is overexpressed in Testis (x19.7), Colon - Transverse (x19.3), Prostate (x5.0), and Pancreas (x4.1).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LINC00668

SOURCE GeneReport for Unigene cluster for LINC00668 Gene:

Hs.253920
genes like me logo Genes that share expression patterns with LINC00668: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC00668 Gene

Orthologs for LINC00668 Gene

Evolution for LINC00668 Gene

ENSEMBL:
Gene Tree for LINC00668 (if available)
TreeFam:
Gene Tree for LINC00668 (if available)

No data available for Orthologs for LINC00668 Gene

Paralogs for LINC00668 Gene

No data available for Paralogs for LINC00668 Gene

Variants for LINC00668 Gene

Additional dbSNP identifiers (rs#s) for LINC00668 Gene

Structural Variations from Database of Genomic Variants (DGV) for LINC00668 Gene

Variant ID Type Subtype PubMed ID
esv2758711 CNV gain 17122850
esv3584943 CNV gain 24956385
esv3641676 CNV loss 21293372
nsv1064175 CNV gain 25217958
nsv576397 CNV gain 21841781
nsv7302 OTHER inversion 18451855
nsv833583 CNV gain 17160897

Additional Variant Information for LINC00668 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC00668

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for LINC00668 Gene

Disorders for LINC00668 Gene

MalaCards: The human disease database

(2) MalaCards diseases for LINC00668 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
oral squamous cell carcinoma
  • mouth squamous cell carcinoma
gastric cancer
  • gastric cancer, somatic
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with LINC00668: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC00668 Gene

Publications for LINC00668 Gene

  1. STAT3-induced long noncoding RNA LINC00668 promotes migration and invasion of non-small cell lung cancer via the miR-193a/KLF7 axis. (PMID: 31150989) An YX … Zhang XJ (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019) 2 3
  2. Long intergenic non-coding RNA 668 regulates VEGFA signaling through inhibition of miR-297 in oral squamous cell carcinoma. (PMID: 28564590) Zhang CZ (Biochemical and biophysical research communications 2017) 2 3
  3. LINC00668 promotes tumorigenesis and progression through sponging miR-188-5p and regulating USP47 in colorectal cancer. (PMID: 31233752) Yan S … Zeng L (European journal of pharmacology 2019) 3
  4. Genome‑wide investigation of the clinical implications and molecular mechanism of long noncoding RNA LINC00668 and protein‑coding genes in hepatocellular carcinoma. (PMID: 31432149) Wang X … Peng T (International journal of oncology 2019) 3
  5. Expression profile analysis identifies the long non-coding RNA landscape and the potential carcinogenic functions of LINC00668 in laryngeal squamous cell carcinoma. (PMID: 30415008) Zhao L … Wang B (Gene 2019) 3

Products for LINC00668 Gene

Sources for LINC00668 Gene