Aliases for LINC00589 Gene

Subcategory (RNA class) for LINC00589 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for LINC00589 Gene

  • Long Intergenic Non-Protein Coding RNA 589 2 3 5
  • LINC00589 2 5 165
  • Tumor Suppressor LncRNA On Chromosome 8p12 2 3
  • TSLNC8 2 3
  • Chromosome 8 Open Reading Frame 75 2
  • NONHSAG049879.2 91
  • HSALNG0064297 164
  • HSALNG0064310 164
  • HSALNG0064295 164
  • C8orf75 3

External Ids for LINC00589 Gene

Previous HGNC Symbols for LINC00589 Gene

  • C8orf75

Previous GeneCards Identifiers for LINC00589 Gene

  • GC08M029531

Summaries for LINC00589 Gene

GeneCards Summary for LINC00589 Gene

LINC00589 (Long Intergenic Non-Protein Coding RNA 589) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with LINC00589 include Hepatocellular Carcinoma.

Additional gene information for LINC00589 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LINC00589 Gene

Genomics for LINC00589 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for LINC00589 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC00589 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for LINC00589 Gene

Genomic Locations for LINC00589 Gene
chr8:29,667,486-29,748,124
(GRCh38/hg38)
Size:
80,639 bases
Orientation:
Minus strand
chr8:29,531,438-29,605,625
(GRCh37/hg19)
Size:
74,188 bases
Orientation:
Minus strand

Genomic View for LINC00589 Gene

Genes around LINC00589 on UCSC Golden Path with GeneCards custom track
LINC00589 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
LINC00589 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC00589 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC00589 Gene

Proteins for LINC00589 Gene

Post-translational modifications for LINC00589 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC00589 Gene

Domains & Families for LINC00589 Gene

Gene Families for LINC00589 Gene

Suggested Antigen Peptide Sequences for LINC00589 Gene

GenScript: Design optimal peptide antigens:
  • C8orf75 protein (Q9BTQ3_HUMAN)
genes like me logo Genes that share domains with LINC00589: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LINC00589 Gene

Function for LINC00589 Gene

Phenotypes From GWAS Catalog for LINC00589 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC00589 Gene

Localization for LINC00589 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC00589 Gene

Pathways & Interactions for LINC00589 Gene

PathCards logo

SuperPathways for LINC00589 Gene

No Data Available

Gene Ontology (GO) - Biological Process for LINC00589 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LINC00589 Gene

Drugs & Compounds for LINC00589 Gene

No Compound Related Data Available

Transcripts for LINC00589 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for LINC00589 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00002AF455_9606 lncRNA 1404 3

Ensembl: ENST00000506121 (view in UCSC) ,

LNCipedia: LINC00589:6,

NONCODE: NONHSAT125826.2,

URS000049EB04_9606 lncRNA 938 3

Ensembl: ENST00000518623 (view in UCSC) ,

LNCipedia: LINC00589:23, LINC00589:8,

NONCODE: NONHSAT125825.2,

URS0000CCE0F1_9606 lncRNA 1398 2

HGNC: 32299,

RefSeq: NR_026765,

URS0000EF4685_9606 lncRNA 1362 1

Ensembl: ENST00000662593 (view in UCSC) ,

URS00008BE891_9606 lncRNA 608 3

LncBook: HSALNT0134756,

LNCipedia: LINC00589:11,

NONCODE: NONHSAT125821.2,

LINC00589 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for LINC00589 Gene

2 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for LINC00589 Gene

No ASD Table

Relevant External Links for LINC00589 Gene

GeneLoc Exon Structure for
LINC00589

Expression for LINC00589 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for LINC00589 Gene

mRNA differential expression in normal tissues according to GTEx for LINC00589 Gene

This gene is overexpressed in Muscle - Skeletal (x7.3) and Minor Salivary Gland (x5.9).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LINC00589

SOURCE GeneReport for Unigene cluster for LINC00589 Gene:

Hs.566911
genes like me logo Genes that share expression patterns with LINC00589: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC00589 Gene

Orthologs for LINC00589 Gene

Evolution for LINC00589 Gene

ENSEMBL:
Gene Tree for LINC00589 (if available)
TreeFam:
Gene Tree for LINC00589 (if available)

No data available for Orthologs for LINC00589 Gene

Paralogs for LINC00589 Gene

No data available for Paralogs for LINC00589 Gene

Variants for LINC00589 Gene

Additional dbSNP identifiers (rs#s) for LINC00589 Gene

Structural Variations from Database of Genomic Variants (DGV) for LINC00589 Gene

Variant ID Type Subtype PubMed ID
nsv478139 CNV novel sequence insertion 20440878

Additional Variant Information for LINC00589 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC00589

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for LINC00589 Gene

Disorders for LINC00589 Gene

MalaCards: The human disease database

(1) MalaCards diseases for LINC00589 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
hepatocellular carcinoma
  • hcc
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with LINC00589: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC00589 Gene

Publications for LINC00589 Gene

  1. Long noncoding RNA TSLNC8 is a tumor suppressor that inactivates the interleukin-6/STAT3 signaling pathway. (PMID: 28746790) Zhang J … He X (Hepatology (Baltimore, Md.) 2018) 2 3
  2. Long Non-Coding RNAs (lncRNAs) Tumor-Suppressive Role of lncRNA on Chromosome 8p12 (TSLNC8) Inhibits Tumor Metastasis and Promotes Apoptosis by Regulating Interleukin 6 (IL-6)/Signal Transducer and Activator of Transcription 3 (STAT3)/Hypoxia-Inducible Factor 1-alpha (HIF-1α) Signaling Pathway in Non-Small Cell Lung Cancer. (PMID: 31601776) Fan H … Hu Z (Medical science monitor : international medical journal of experimental and clinical research 2019) 3
  3. Long noncoding RNA TSLNC8 suppresses cell proliferation and metastasis and promotes cell apoptosis in human glioma. (PMID: 30387847) Chen D … Yu X (Molecular medicine reports 2018) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for LINC00589 Gene

Sources for LINC00589 Gene