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Aliases for LINC00520 Gene

Subcategory (RNA class) for LINC00520 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for LINC00520 Gene

  • Long Intergenic Non-Protein Coding RNA 520 2 3 5
  • Chromosome 14 Open Reading Frame 34 2
  • C14orf34 3

External Ids for LINC00520 Gene

Previous HGNC Symbols for LINC00520 Gene

  • C14orf34

Previous GeneCards Identifiers for LINC00520 Gene

  • GC14M056248

Summaries for LINC00520 Gene

GeneCards Summary for LINC00520 Gene

LINC00520 (Long Intergenic Non-Protein Coding RNA 520) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with LINC00520 include Breast Cancer.

Additional gene information for LINC00520 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC00520 Gene

Genomics for LINC00520 Gene

GeneHancer (GH) Regulatory Elements for LINC00520 Gene

Promoters and enhancers for LINC00520 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14J055794 Enhancer 0.7 ENCODE dbSUPER 650.7 +1.8 1790 0.2 FOSL1 JUND JUN ZSCAN5C STAT3 FOSL2 FOS LINC00520 PELI2 RPL13AP3 GC14P055769
GH14J055798 Enhancer 0.5 ENCODE 650.7 -1.9 -1890 0.2 GATA3 CLOCK HES1 FOXA1 LINC00520 PIR35523
GH14J055802 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -8.7 -8704 6.3 PKNOX1 ATF1 FOXA2 BRCA1 YY1 GTF3C2 TCF12 GLIS2 GATA2 ATF7 LOC105370515 ATG14 MAPK1IP1L SOCS4 LINC00520 PIR35523
GH14J055779 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.4 +16.3 16257 2.6 MXI1 SMAD1 NFIB TAL1 EBF1 RAD21 NCOR1 STAT1 SOX6 CBFA2T3 GC14P055769 RPL13AP3 LINC00520
GH14J055790 Enhancer 1 Ensembl ENCODE dbSUPER 0.4 +5.5 5459 1.8 SOX6 JUN CEBPB CEBPG EP300 NR2F2 ATF4 MAFK TBPL2 LINC00520 GC14P055769 RPL13AP3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC00520 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC00520 Gene

Genomic Locations for LINC00520 Gene
chr14:55,781,135-55,796,688
(GRCh38/hg38)
Size:
15,554 bases
Orientation:
Minus strand
chr14:56,247,853-56,263,406
(GRCh37/hg19)
Size:
15,554 bases
Orientation:
Minus strand

Genomic View for LINC00520 Gene

Genes around LINC00520 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC00520 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC00520 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC00520 Gene

Proteins for LINC00520 Gene

Post-translational modifications for LINC00520 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC00520 Gene

Domains & Families for LINC00520 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC00520 Gene

Function for LINC00520 Gene

Phenotypes From GWAS Catalog for LINC00520 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC00520 Gene

Localization for LINC00520 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC00520 Gene

Pathways & Interactions for LINC00520 Gene

SuperPathways for LINC00520 Gene

No Data Available

Interacting Proteins for LINC00520 Gene

Gene Ontology (GO) - Biological Process for LINC00520 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC00520 Gene

Drugs & Compounds for LINC00520 Gene

No Compound Related Data Available

Transcripts for LINC00520 Gene

mRNA/cDNA for LINC00520 Gene

(2) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(8) RNA Central transcripts :

Unigene Clusters for LINC00520 Gene

Long intergenic non-protein coding RNA 520:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for LINC00520 Gene

No ASD Table

Relevant External Links for LINC00520 Gene

GeneLoc Exon Structure for
LINC00520
ECgene alternative splicing isoforms for
LINC00520

Expression for LINC00520 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC00520 Gene

mRNA differential expression in normal tissues according to GTEx for LINC00520 Gene

This gene is overexpressed in Stomach (x12.8), Colon - Transverse (x4.3), and Esophagus - Mucosa (x4.2).

NURSA nuclear receptor signaling pathways regulating expression of LINC00520 Gene:

LINC00520

SOURCE GeneReport for Unigene cluster for LINC00520 Gene:

Hs.569345
genes like me logo Genes that share expression patterns with LINC00520: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC00520 Gene

Orthologs for LINC00520 Gene

Evolution for LINC00520 Gene

ENSEMBL:
Gene Tree for LINC00520 (if available)
TreeFam:
Gene Tree for LINC00520 (if available)

No data available for Orthologs for LINC00520 Gene

Paralogs for LINC00520 Gene

No data available for Paralogs for LINC00520 Gene

Variants for LINC00520 Gene

Sequence variations from dbSNP and Humsavar for LINC00520 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000154850 -- 55,785,185(-) G/A intron_variant
rs1000228588 -- 55,786,391(-) T/C intron_variant
rs1000361995 -- 55,790,204(-) T/C/G intron_variant
rs1000860625 -- 55,796,552(-) T/C intron_variant
rs1000935092 -- 55,794,539(-) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for LINC00520 Gene

Variant ID Type Subtype PubMed ID
esv3634579 CNV gain 21293372
esv3892549 CNV gain 25118596
nsv472403 CNV novel sequence insertion 20440878
nsv832804 CNV gain 17160897

Additional Variant Information for LINC00520 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC00520

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for LINC00520 Gene

Disorders for LINC00520 Gene

MalaCards: The human disease database

(1) MalaCards diseases for LINC00520 Gene - From: LncRNADisease

Disorder Aliases PubMed IDs
breast cancer
  • breast cancer, familial
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for LINC00520

genes like me logo Genes that share disorders with LINC00520: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC00520 Gene

Publications for LINC00520 Gene

  1. LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer. (PMID: 27626181) Henry WS … Toker A (Oncotarget 2016) 2 3 58
  2. Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function. (PMID: 29348663) Miao Y … Chen Z (Nature communications 2018) 3 58
  3. Genome-wide association studies and heritability estimates of body mass index related phenotypes in Bangladeshi adults. (PMID: 25133637) Scannell Bryan M … Ahsan H (PloS one 2014) 3 58
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3 58

Products for LINC00520 Gene

Sources for LINC00520 Gene

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