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Aliases for LINC00319 Gene

Subcategory (RNA class) for LINC00319 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for LINC00319 Gene

  • Long Intergenic Non-Protein Coding RNA 319 2 3 5
  • Chromosome 21 Open Reading Frame 125 2
  • Non-Protein Coding RNA 319 2
  • NCRNA00319 3
  • C21orf125 3
  • PRED49 3

External Ids for LINC00319 Gene

Previous HGNC Symbols for LINC00319 Gene

  • C21orf125
  • NCRNA00319

Previous GeneCards Identifiers for LINC00319 Gene

  • GC21P044869

Summaries for LINC00319 Gene

GeneCards Summary for LINC00319 Gene

LINC00319 (Long Intergenic Non-Protein Coding RNA 319) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with LINC00319 include Lung Cancer Susceptibility 3.

Additional gene information for LINC00319 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC00319 Gene

Genomics for LINC00319 Gene

GeneHancer (GH) Regulatory Elements for LINC00319 Gene

Promoters and enhancers for LINC00319 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J043438 Promoter/Enhancer 2.2 FANTOM5 Ensembl ENCODE dbSUPER 10.8 -3.1 -3054 9.5 ZNF652 ELF3 CEBPG RERE AHR MAFK TFE3 SP1 HNF1A PPARG LINC00319 RRP1B SIK1
GH21J043450 Enhancer 1.1 Ensembl ENCODE dbSUPER 10.6 +4.8 4764 2.7 SP1 RXRA FOXA2 SCRT2 JUND FOS ATF3 YY1 POLR2A ZFHX2 LINC00319 PDXK GC21P043455
GH21J043409 Enhancer 1.4 FANTOM5 ENCODE dbSUPER 6.8 -35.5 -35549 4 ZNF687 NCOA3 MAFK SP1 MLLT1 IKZF1 CREB1 POLR2A ZBTB33 NRF1 SIK1 ENSG00000184441 CFAP410 LINC00319 ICOSLG LOC105377137
GH21J043435 Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 7.2 -10.1 -10114 1.5 ZNF7 GLIS1 ZNF146 KLF1 FRGCA LINC00319 SIK1
GH21J043419 Enhancer 0.8 ENCODE dbSUPER 7.3 -26.8 -26829 1 ZBTB33 SP2 POLR2A ZFHX2 ZFP69B FOSL2 SIN3A CTCF FOS RAD21 LINC00319 PDXK SIK1 LOC105377137
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC00319 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC00319 Gene

Genomic Locations for LINC00319 Gene
chr21:43,446,601-43,453,902
(GRCh38/hg38)
Size:
7,302 bases
Orientation:
Plus strand
chr21:44,866,481-44,873,773
(GRCh37/hg19)
Size:
7,293 bases
Orientation:
Plus strand

Genomic View for LINC00319 Gene

Genes around LINC00319 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC00319 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC00319 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC00319 Gene

Proteins for LINC00319 Gene

Post-translational modifications for LINC00319 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC00319 Gene

Domains & Families for LINC00319 Gene

Gene Families for LINC00319 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC00319: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC00319 Gene

Function for LINC00319 Gene

Phenotypes From GWAS Catalog for LINC00319 Gene

Phenotypes for LINC00319 Gene

GenomeRNAi human phenotypes for LINC00319:
genes like me logo Genes that share phenotypes with LINC00319: view

Animal Model Products

CRISPR Products

miRNA for LINC00319 Gene

miRTarBase miRNAs that target LINC00319

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LINC00319

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for LINC00319 Gene

Localization for LINC00319 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC00319 Gene

Pathways & Interactions for LINC00319 Gene

PathCards logo

SuperPathways for LINC00319 Gene

No Data Available

Interacting Proteins for LINC00319 Gene

Gene Ontology (GO) - Biological Process for LINC00319 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC00319 Gene

Drugs & Compounds for LINC00319 Gene

No Compound Related Data Available

Transcripts for LINC00319 Gene

mRNA/cDNA for LINC00319 Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

Unigene Clusters for LINC00319 Gene

Long intergenic non-protein coding RNA 319:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LINC00319

Alternative Splicing Database (ASD) splice patterns (SP) for LINC00319 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4
SP1: -
SP2:

Relevant External Links for LINC00319 Gene

GeneLoc Exon Structure for
LINC00319
ECgene alternative splicing isoforms for
LINC00319

Expression for LINC00319 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC00319 Gene

mRNA differential expression in normal tissues according to GTEx for LINC00319 Gene

This gene is overexpressed in Liver (x6.2) and Pancreas (x5.4).

NURSA nuclear receptor signaling pathways regulating expression of LINC00319 Gene:

LINC00319

SOURCE GeneReport for Unigene cluster for LINC00319 Gene:

Hs.146127
genes like me logo Genes that share expression patterns with LINC00319: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC00319 Gene

Orthologs for LINC00319 Gene

Evolution for LINC00319 Gene

ENSEMBL:
Gene Tree for LINC00319 (if available)
TreeFam:
Gene Tree for LINC00319 (if available)

No data available for Orthologs for LINC00319 Gene

Paralogs for LINC00319 Gene

No data available for Paralogs for LINC00319 Gene

Variants for LINC00319 Gene

Sequence variations from dbSNP and Humsavar for LINC00319 Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1000042974 -- 43,446,112(+) C/G upstream_transcript_variant
rs1000074311 -- 43,445,942(+) T/C upstream_transcript_variant
rs1000228189 -- 43,450,189(+) G/A intron_variant
rs1001089997 -- 43,446,740(+) GG/G non_coding_transcript_variant
rs1001712945 -- 43,445,110(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for LINC00319 Gene

Variant ID Type Subtype PubMed ID
dgv7871n54 CNV loss 21841781
dgv7872n54 CNV loss 21841781
esv2666871 CNV deletion 23128226
nsv1056684 CNV gain 25217958
nsv459288 CNV loss 19166990
nsv470901 CNV loss 18288195
nsv483099 CNV gain 15286789
nsv516339 CNV gain+loss 19592680
nsv587686 CNV loss 21841781
nsv828901 CNV gain 20364138
nsv953640 CNV deletion 24416366

Additional Variant Information for LINC00319 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC00319

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for LINC00319 Gene

Disorders for LINC00319 Gene

MalaCards: The human disease database

(1) MalaCards diseases for LINC00319 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
lung cancer susceptibility 3
  • lncr3
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for LINC00319

genes like me logo Genes that share disorders with LINC00319: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC00319 Gene

Publications for LINC00319 Gene

  1. Long intergenic non-protein coding RNA 319 aggravates lung adenocarcinoma carcinogenesis by modulating miR-450b-5p/EZH2. (PMID: 29408583) Zhang ZW … Sun CC (Gene 2018) 2 3 58
  2. Long Intergenic Noncoding RNA 319 (linc00319) Promotes Cell Proliferation and Invasion in Lung Cancer Cells by Directly Downregulating the Tumor Suppressor MiR-32. (PMID: 28800794) Zhou B … Li X (Oncology research 2017) 2 3 58
  3. Long non-coding RNA 319 facilitates nasopharyngeal carcinoma carcinogenesis through regulation of miR-1207-5p/KLF12 axis. (PMID: 30243935) Song P … Yin SC (Gene 2019) 3 58
  4. LncRNA LINC00319 accelerates ovarian cancer progression through miR-423-5p/NACC1 pathway. (PMID: 30442370) Du W … Sun Q (Biochemical and biophysical research communications 2018) 3 58
  5. Functional analysis and identification of cis-regulatory elements of human chromosome 21 gene promoters. (PMID: 20494980) Warnatz HJ … Yaspo ML (Nucleic acids research 2010) 3 58

Products for LINC00319 Gene

Sources for LINC00319 Gene

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