Aliases for LINC00161 Gene

Subcategory (RNA class) for LINC00161 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for LINC00161 Gene

  • Long Intergenic Non-Protein Coding RNA 161 2 3 5
  • LINC00161 2 168
  • Chromosome 21 Open Reading Frame 100 2
  • Non-Protein Coding RNA 161 2
  • NONHSAG032605 92
  • HSALNG0132500 167
  • Linc-USP16 3
  • NCRNA00161 3
  • C21orf100 3

External Ids for LINC00161 Gene

Previous HGNC Symbols for LINC00161 Gene

  • C21orf100
  • NCRNA00161

Previous GeneCards Identifiers for LINC00161 Gene

  • GC21P029912

Summaries for LINC00161 Gene

GeneCards Summary for LINC00161 Gene

LINC00161 (Long Intergenic Non-Protein Coding RNA 161) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with LINC00161 include Osteogenic Sarcoma.

Additional gene information for LINC00161 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LINC00161 Gene

Genomics for LINC00161 Gene

GeneHancer (GH) Regulatory Elements for LINC00161 Gene

Promoters and enhancers for LINC00161 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J028536 Enhancer 0.8 Ensembl ENCODE 500.7 +0.8 794 5.7 JUND FOS ATF2 USF1 EZH2 GATA3 PRDM1 GATA2 ZFP37 JUN LINC00161 piR-36393-329 lnc-USP16-11 ENSG00000232855
GH21J029381 Enhancer 0.9 Ensembl ENCODE 4.3 +843.9 843942 2 ZNF217 ZSCAN5C JUND FOS ZNF10 GATAD2B CTBP1 ESR1 NEUROD1 JUN LINC00161 BACH1-AS1 RF01210-239 BACH1 GRIK1-AS2
GH21J028521 Enhancer 0.7 Ensembl ENCODE 0.4 -15.7 -15658 2.4 CTCF NR2F2 FOS RAD21 GATA2 JUN POLR2A SMC3 RF00017-3680 lnc-USP16-11 LINC00161 ENSG00000232855
GH21J028549 Enhancer 0.4 Ensembl 0.4 +11.7 11742 0.4 JUND GATA3 GATA2 CCT8 LINC00161 piR-36393-329 lnc-USP16-11 ENSG00000232855
GH21J028542 Enhancer 0.2 Ensembl 0.7 +4.6 4642 1 LINC00161 piR-36393-329 lnc-USP16-11 ENSG00000232855
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC00161 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC00161 Gene

Genomic Locations for LINC00161 Gene
chr21:28,538,459-28,547,509
(GRCh38/hg38)
Size:
9,051 bases
Orientation:
Plus strand
chr21:29,911,640-29,912,677
(GRCh37/hg19)
Size:
1,038 bases
Orientation:
Plus strand

Genomic View for LINC00161 Gene

Genes around LINC00161 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC00161 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC00161 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC00161 Gene

Proteins for LINC00161 Gene

Post-translational modifications for LINC00161 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC00161 Gene

Domains & Families for LINC00161 Gene

Gene Families for LINC00161 Gene

genes like me logo Genes that share domains with LINC00161: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LINC00161 Gene

Function for LINC00161 Gene

Phenotypes From GWAS Catalog for LINC00161 Gene

Phenotypes for LINC00161 Gene

GenomeRNAi human phenotypes for LINC00161:
genes like me logo Genes that share phenotypes with LINC00161: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC00161 Gene

Localization for LINC00161 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LINC00161 gene
Compartment Confidence
plasma membrane 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC00161 Gene

Pathways & Interactions for LINC00161 Gene

PathCards logo

SuperPathways for LINC00161 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for LINC00161 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LINC00161 Gene

Drugs & Compounds for LINC00161 Gene

No Compound Related Data Available

Transcripts for LINC00161 Gene

mRNA/cDNA for LINC00161 Gene

5 RNACentral transcripts :
2 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 NONCODE transcripts :
3 LncBook transcripts :
4 LNCipedia transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for LINC00161 Gene

No ASD Table

Relevant External Links for LINC00161 Gene

GeneLoc Exon Structure for
LINC00161

Expression for LINC00161 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for LINC00161 Gene

mRNA differential expression in normal tissues according to GTEx for LINC00161 Gene

This gene is overexpressed in Prostate (x18.1).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LINC00161

SOURCE GeneReport for Unigene cluster for LINC00161 Gene:

Hs.438549
genes like me logo Genes that share expression patterns with LINC00161: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC00161 Gene

Orthologs for LINC00161 Gene

Evolution for LINC00161 Gene

ENSEMBL:
Gene Tree for LINC00161 (if available)
TreeFam:
Gene Tree for LINC00161 (if available)

No data available for Orthologs for LINC00161 Gene

Paralogs for LINC00161 Gene

No data available for Paralogs for LINC00161 Gene

Variants for LINC00161 Gene

Additional dbSNP identifiers (rs#s) for LINC00161 Gene

Structural Variations from Database of Genomic Variants (DGV) for LINC00161 Gene

Variant ID Type Subtype PubMed ID
nsv1057761 CNV gain 25217958

Additional Variant Information for LINC00161 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC00161

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for LINC00161 Gene

Disorders for LINC00161 Gene

MalaCards: The human disease database

(1) MalaCards diseases for LINC00161 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
osteogenic sarcoma
  • osteosarcoma; osrc
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for LINC00161

genes like me logo Genes that share disorders with LINC00161: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC00161 Gene

Publications for LINC00161 Gene

  1. Long non-coding RNA LINC00161 sensitises osteosarcoma cells to cisplatin-induced apoptosis by regulating the miR-645-IFIT2 axis. (PMID: 27609068) Wang Y … Zhang W (Cancer letters 2016) 2 3 54
  2. Nineteen additional unpredicted transcripts from human chromosome 21. (PMID: 12036297) Reymond A … Antonarakis SE (Genomics 2002) 2 3 54
  3. Linc00161 regulated the drug resistance of ovarian cancer by sponging microRNA-128 and modulating MAPK1. (PMID: 30556928) Xu M … Lu S (Molecular carcinogenesis 2019) 3 54
  4. Long Non-Coding RNA Linc-USP16 Functions As a Tumour Suppressor in Hepatocellular Carcinoma by Regulating PTEN Expression. (PMID: 29179215) Sui J … Sun D (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017) 3 54
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 54

Products for LINC00161 Gene

Sources for LINC00161 Gene