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Aliases for LINC00114 Gene

Subcategory (RNA class) for LINC00114 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for LINC00114 Gene

  • Long Intergenic Non-Protein Coding RNA 114 2 3 5
  • NCRNA00114 3 4
  • C21orf24 3 4
  • Putative Uncharacterized Protein Encoded By LINC00114 4
  • Chromosome 21 Open Reading Frame 24 2
  • Non-Protein Coding RNA 114 2

External Ids for LINC00114 Gene

Previous HGNC Symbols for LINC00114 Gene

  • C21orf24
  • NCRNA00114

Previous GeneCards Identifiers for LINC00114 Gene

  • GC21M040111

Summaries for LINC00114 Gene

GeneCards Summary for LINC00114 Gene

LINC00114 (Long Intergenic Non-Protein Coding RNA 114) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with LINC00114 include Meningioma, Familial.

Additional gene information for LINC00114 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LINC00114 Gene

Genomics for LINC00114 Gene

GeneHancer (GH) Regulatory Elements for LINC00114 Gene

Promoters and enhancers for LINC00114 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J038755 Enhancer 1.3 FANTOM5 ENCODE dbSUPER 10.8 +17.1 17093 2.5 ELF3 ZNF121 ZNF384 SP1 FOSL2 CREB1 RNF2 ZBTB8A RFX1 PRDM12 HMGN1 PSMG1 LCA5L LINC00114 GC21M038495
GH21J038906 Promoter/Enhancer 2.1 FANTOM5 Ensembl ENCODE dbSUPER 5.5 -138.0 -137964 9.6 ZNF473 MTA3 ZNF652 ELF3 MLLT1 GTF2F1 NFIB ZSCAN21 NCOA3 CDC5L HMGN1 LCA5L PSMG1 LINC00114 RPSAP64 LOC400867 ENSG00000205622
GH21J038759 Enhancer 0.8 ENCODE dbSUPER 10.1 +13.5 13533 0.6 ZNF639 PKNOX1 NFE2 ZSCAN29 MAFG MAFK NFIC RCOR1 JUND BHLHE40 LINC00114 GC21M038495
GH21J038750 Enhancer 0.8 ENCODE dbSUPER 10.2 +21.1 21051 3.1 ZNF652 SP1 PKNOX1 ZBTB25 NR2F2 ZNF189 POLR2A MYC FOXA3 ERF LINC00114 GC21M038495
GH21J038761 Enhancer 0.4 dbSUPER 10.8 +11.7 11707 1.4 PRDM1 ZNF512 LINC00114 GC21M038495
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LINC00114 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LINC00114 Gene

Genomic Locations for LINC00114 Gene
chr21:38,738,955-38,773,477
(GRCh38/hg38)
Size:
34,523 bases
Orientation:
Minus strand
chr21:40,110,879-40,145,401
(GRCh37/hg19)
Size:
34,523 bases
Orientation:
Minus strand

Genomic View for LINC00114 Gene

Genes around LINC00114 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LINC00114 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LINC00114 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LINC00114 Gene

Proteins for LINC00114 Gene

  • Protein details for LINC00114 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6XXX2-CU024_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by LINC00114
    Protein Accession:
    Q6XXX2

    Protein attributes for LINC00114 Gene

    Size:
    140 amino acids
    Molecular mass:
    15753 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LINC00114 Gene

Post-translational modifications for LINC00114 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LINC00114 Gene

Domains & Families for LINC00114 Gene

Protein Domains for LINC00114 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LINC00114: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LINC00114 Gene

Function for LINC00114 Gene

Phenotypes From GWAS Catalog for LINC00114 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LINC00114

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LINC00114 Gene

Localization for LINC00114 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LINC00114 Gene

Pathways & Interactions for LINC00114 Gene

PathCards logo

SuperPathways for LINC00114 Gene

No Data Available

Interacting Proteins for LINC00114 Gene

Gene Ontology (GO) - Biological Process for LINC00114 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LINC00114 Gene

Drugs & Compounds for LINC00114 Gene

No Compound Related Data Available

Transcripts for LINC00114 Gene

mRNA/cDNA for LINC00114 Gene

(1) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(5) RNA Central transcripts :

Unigene Clusters for LINC00114 Gene

Long intergenic non-protein coding RNA 114:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LINC00114

Alternative Splicing Database (ASD) splice patterns (SP) for LINC00114 Gene

No ASD Table

Relevant External Links for LINC00114 Gene

GeneLoc Exon Structure for
LINC00114
ECgene alternative splicing isoforms for
LINC00114

Expression for LINC00114 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LINC00114 Gene

mRNA differential expression in normal tissues according to GTEx for LINC00114 Gene

This gene is overexpressed in Colon - Transverse (x9.7), Small Intestine - Terminal Ileum (x7.5), Testis (x4.9), and Cervix - Endocervix (x4.3).

NURSA nuclear receptor signaling pathways regulating expression of LINC00114 Gene:

LINC00114

SOURCE GeneReport for Unigene cluster for LINC00114 Gene:

Hs.278704

mRNA Expression by UniProt/SwissProt for LINC00114 Gene:

Q6XXX2-CU024_HUMAN
Tissue specificity: Expressed in a range of cell lines, including B-cell lymphoma and prostate.
genes like me logo Genes that share expression patterns with LINC00114: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LINC00114 Gene

Orthologs for LINC00114 Gene

Evolution for LINC00114 Gene

ENSEMBL:
Gene Tree for LINC00114 (if available)
TreeFam:
Gene Tree for LINC00114 (if available)

No data available for Orthologs for LINC00114 Gene

Paralogs for LINC00114 Gene

No data available for Paralogs for LINC00114 Gene

Variants for LINC00114 Gene

Sequence variations from dbSNP and Humsavar for LINC00114 Gene

SNP ID Clin Chr 21 pos Variation AA Info Type
rs1000068649 -- 38,744,446(-) C/T intron_variant
rs1000081987 -- 38,750,109(-) AAAAA/AAAA intron_variant
rs1000201140 -- 38,752,354(-) G/A intron_variant
rs1000213749 -- 38,767,378(-) G/A intron_variant
rs1000214375 -- 38,768,122(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for LINC00114 Gene

Variant ID Type Subtype PubMed ID
dgv4431n100 CNV gain 25217958
dgv4432n100 CNV gain 25217958
dgv534n27 CNV gain 19166990
dgv7833n54 CNV gain 21841781
esv3568191 CNV loss 25503493
esv3575390 CNV gain 25503493
esv3647006 CNV loss 21293372
esv3647007 CNV gain 21293372
esv3647008 CNV loss 21293372
esv3647009 CNV loss 21293372
esv3893409 CNV gain 25118596
nsv1058591 CNV gain 25217958
nsv1160714 CNV duplication 26073780
nsv3517 CNV insertion 18451855
nsv470900 CNV gain 18288195
nsv516348 CNV gain 19592680
nsv953364 CNV duplication 24416366
nsv954290 CNV deletion 24416366

Additional Variant Information for LINC00114 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LINC00114

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for LINC00114 Gene

Disorders for LINC00114 Gene

MalaCards: The human disease database

(1) MalaCards diseases for LINC00114 Gene - From: DISEASES

Disorder Aliases PubMed IDs
meningioma, familial
  • meningioma, familial, susceptibility to
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for LINC00114

genes like me logo Genes that share disorders with LINC00114: view

No data available for UniProtKB/Swiss-Prot and Genatlas for LINC00114 Gene

Publications for LINC00114 Gene

  1. Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16. (PMID: 14693372) Owczarek CM … Hertzog PJ (Gene 2004) 3 4 58
  2. The DNA sequence of human chromosome 21. (PMID: 10830953) Hattori M … Chromosome 21 mapping and sequencing consortium (Nature 2000) 3 58

Products for LINC00114 Gene

Sources for LINC00114 Gene

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