Aliases for LIN9 Gene
External Ids for LIN9 Gene
Previous GeneCards Identifiers for LIN9 Gene
This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
GeneCards Summary for LIN9 Gene
LIN9 (Lin-9 DREAM MuvB Core Complex Component) is a Protein Coding gene. Diseases associated with LIN9 include Algoneurodystrophy and Hyperlipoproteinemia, Type I. Among its related pathways are Cell cycle Cell cycle (generic schema) and Regulation of PLK1 Activity at G2/M Transition.
UniProtKB/Swiss-Prot Summary for LIN9 Gene
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.