LIFR-AS1 Gene (RNA Gene)

LIFR Antisense RNA 1

GC05P038559
GIFtS:
13
See more...

Aliases for LIFR-AS1 Gene

Data sources for LIFR-AS1 Gene:

Subcategory (RNA class) for LIFR-AS1 Gene

lncRNA

Aliases for LIFR-AS1 Gene

External Ids for LIFR-AS1 Gene

Summaries for LIFR-AS1 Gene

GeneCards Summary for LIFR-AS1 Gene

LIFR-AS1 (LIFR Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for LIFR-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LIFR-AS1 Gene

Genomics for LIFR-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for LIFR-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH05J038552 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 258.7 -1.4 -1370 5.3 ZSCAN16 TBP ZBTB10 MBD2 NONO ZIC2 ZNF610 CEBPB ZNF623 ELK1 LIFR LIFR-AS1 ENSG00000251257 EGFLAM-AS1 ENSG00000248234 EGFLAM-AS2 EGFLAM MIR3650 lnc-RICTOR-6
GH05J038594 Promoter/Enhancer 1.2 EPDnew Ensembl ENCODE 11.6 +38.9 38853 1.6 NFE2 GLIS1 ZNF600 LIFR LIFR-AS1 lnc-LIFR-6 HSALNG0041284 EGFLAM
GH05J038597 Enhancer 1 Ensembl ENCODE 10.8 +43.9 43936 7.4 FEZF1 DEK BRCA1 BHLHE40 ZIC2 CEBPB FOXA2 ZNF639 MAX EP300 LIFR-AS1 LIFR lnc-LIFR-6 HSALNG0041284 EGFLAM
GH05J038607 Enhancer 1 Ensembl ENCODE 9.5 +51.1 51095 1.7 ZSCAN16 FEZF1 DEK CEBPB ZNF513 MAX VEZF1 EP300 TAL1 RAD21 LIFR lnc-LIFR-6 LINC01265 OSMR LIFR-AS1 HSALNG0041284 EGFLAM
GH05J038633 Enhancer 0.7 ENCODE 9.8 +78.7 78658 4.2 ZNF217 BRCA1 SIX4 CEBPB EP300 RAD21 CTBP1 RFX5 SMC3 STAT3 LIFR LIFR-AS1 ENSG00000251189 piR-46002-460 OSMR
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LIFR-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for LIFR-AS1 Gene

Latest Assembly
chr5:38,556,765-38,719,004
(GRCh38/hg38)
Size:
162,240 bases
Orientation:
Plus strand

Previous Assembly
chr5:38,556,888-38,671,318
(GRCh37/hg19 by Entrez Gene)
Size:
114,431 bases
Orientation:
Plus strand

chr5:38,556,888-38,671,318
(GRCh37/hg19 by Ensembl)
Size:
114,431 bases
Orientation:
Plus strand

Genomic View for LIFR-AS1 Gene

Genes around LIFR-AS1 on UCSC Golden Path with GeneCards custom track
LIFR-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
LIFR-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LIFR-AS1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for LIFR-AS1 Gene

Proteins for LIFR-AS1 Gene

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  2. Protein products for research
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Post-translational modifications for LIFR-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LIFR-AS1 Gene

Domains & Families for LIFR-AS1 Gene

Gene Families for LIFR-AS1 Gene

HGNC:
genes like me logo Genes that share domains with LIFR-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LIFR-AS1 Gene

Function for LIFR-AS1 Gene

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  2. CRISPR products for research
  3. miRNA products for research
  4. Inhibitory RNAs for research
  5. Clone products for research
  6. Cell Lines for research

Phenotypes From GWAS Catalog for LIFR-AS1 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LIFR-AS1 Gene

Localization for LIFR-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LIFR-AS1 Gene

Pathways & Interactions for LIFR-AS1 Gene

PathCards logo

SuperPathways for LIFR-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for LIFR-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LIFR-AS1 Gene

Drugs & Compounds for LIFR-AS1 Gene

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  1. Drug products for research
No Compound Related Data Available

Transcripts for LIFR-AS1 Gene

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  2. miRNA products for research
  3. Inhibitory RNAs for research
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Non-coding RNA (ncRNA) Transcripts from RNAcentral for LIFR-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000490DBB_9606 lncRNA 3806 4

RefSeq: NR_103553,

Ensembl: ENST00000500733 (view in UCSC) ,

LNCipedia: LIFR-AS1:2,

NONCODE: NONHSAT101098.2,

URS000058F4A1_9606 lncRNA 685 4

Ensembl: ENST00000514291 (view in UCSC) ,

LncBook: HSALNT0086803,

LNCipedia: LIFR-AS1:6,

NONCODE: NONHSAT101100.2,

URS000018432E_9606 lncRNA 1351 2

Ensembl: ENST00000500817 (view in UCSC) ,

LNCipedia: LIFR-AS1:5,

URS0000EF2103_9606 lncRNA 3626 1

Ensembl: ENST00000670079 (view in UCSC) ,

URS0000EF190F_9606 lncRNA 3542 1

Ensembl: ENST00000660661 (view in UCSC) ,

LIFR-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for LIFR-AS1 Gene

3 NCBI additional mRNA sequence :

CRISPR products for research

Alternative Splicing Database (ASD) splice patterns (SP) for LIFR-AS1 Gene

No ASD Table

Relevant External Links for LIFR-AS1 Gene

GeneLoc Exon Structure for
LIFR-AS1

Expression for LIFR-AS1 Gene

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  1. Primer products for research
  2. Gene Expression Assays for research

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for LIFR-AS1 Gene

mRNA expression in normal human tissues for LIFR-AS1 Gene
mRNA expression by GTEx for LIFR-AS1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LIFR-AS1

SOURCE GeneReport for Unigene cluster for LIFR-AS1 Gene:

Hs.657602
genes like me logo Genes that share expression patterns with LIFR-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LIFR-AS1 Gene

Orthologs for LIFR-AS1 Gene

Evolution for LIFR-AS1 Gene

ENSEMBL:
Gene Tree for LIFR-AS1 (if available)
TreeFam:
Gene Tree for LIFR-AS1 (if available)

No data available for Orthologs for LIFR-AS1 Gene

Paralogs for LIFR-AS1 Gene

No data available for Paralogs for LIFR-AS1 Gene

Variants for LIFR-AS1 Gene

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  1. SNP Genotyping and Copy Number Assays for research

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LIFR-AS1 Gene

SNP ID Clinical significance and condition Chr 05 pos Variation AA Info Type
rs186528221 Benign: Stüve-Wiedemann syndrome 38,594,967(+) T/A
NM_002310.6(LIFR):c.-20+294A>T 		NON_CODING_TRANSCRIPT_VARIANT,INTRON
rs373489850 Uncertain Significance: Stüve-Wiedemann syndrome 38,595,380(+) C/T
NM_002310.6(LIFR):c.-139G>A 		FIVE_PRIME_UTR
rs55892837 Uncertain Significance: Stüve-Wiedemann syndrome 38,595,370(+) A/C
NM_002310.6(LIFR):c.-129T>G 		FIVE_PRIME_UTR
rs559787973 Uncertain Significance: Stüve-Wiedemann syndrome 38,595,331(+) A/G
NM_002310.6(LIFR):c.-90T>C 		FIVE_PRIME_UTR
rs573436558 Uncertain Significance: Stüve-Wiedemann syndrome 38,595,359(+) C/T
NM_002310.6(LIFR):c.-118G>A 		FIVE_PRIME_UTR

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for LIFR-AS1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for LIFR-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv1594e212 CNV loss 25503493
dgv9729n54 CNV loss 21841781
esv22263 CNV loss 19812545
esv3570081 CNV loss 25503493
esv3604761 CNV gain 21293372
esv3604771 CNV gain 21293372
nsv1112871 CNV deletion 24896259
nsv1136993 CNV deletion 24896259
nsv597856 CNV gain+loss 21841781
nsv597857 CNV gain 21841781

Additional Variant Information for LIFR-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
LIFR-AS1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for LIFR-AS1 Gene

Disorders for LIFR-AS1 Gene

Additional Disease Information for LIFR-AS1

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform

No disorders were found for LIFR-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LIFR-AS1 Gene

Publications for LIFR-AS1 Gene

  1. Functional role of a long non-coding RNA LIFR-AS1/miR-29a/TNFAIP3 axis in colorectal cancer resistance to pohotodynamic therapy. (PMID: 29807108) Liu K … Xiong L (Biochimica et biophysica acta. Molecular basis of disease 2018) 2 3
  2. Identifying the crosstalk of dysfunctional pathways mediated by lncRNAs in breast cancer subtypes. (PMID: 26725846) Wang L … Li X (Molecular bioSystems 2016) 2 3
  3. LIFR-AS1 modulates Sufu to inhibit cell proliferation and migration by miR-197-3p in breast cancer. (PMID: 31127025) Xu F … Hu C (Bioscience reports 2019) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

ExternalLinks

View latest publications for LIFR-AS1 gene in Mastermind

Products for LIFR-AS1 Gene

Sources for LIFR-AS1 Gene