Aliases for LHX9 Gene
External Ids for LHX9 Gene
Previous GeneCards Identifiers for LHX9 Gene
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
GeneCards Summary for LHX9 Gene
LHX9 (LIM Homeobox 9) is a Protein Coding gene. Diseases associated with LHX9 include Gonadal Agenesis and 46,Xy Sex Reversal. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and transcription corepressor activity. An important paralog of this gene is LHX2.
UniProtKB/Swiss-Prot Summary for LHX9 Gene
Involved in gonadal development.