Aliases for LHX5 Gene
External Ids for LHX5 Gene
Previous GeneCards Identifiers for LHX5 Gene
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice. [provided by RefSeq, Jul 2008]
GeneCards Summary for LHX5 Gene
LHX5 (LIM Homeobox 5) is a Protein Coding gene. Diseases associated with LHX5 include Scapuloperoneal Spinal Muscular Atrophy and Scapuloperoneal Myopathy. Among its related pathways are Neural Crest Differentiation and Signaling pathways regulating pluripotency of stem cells. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is LHX1.
UniProtKB/Swiss-Prot Summary for LHX5 Gene
Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.