Aliases for LHX2 Gene
External Ids for LHX2 Gene
Previous GeneCards Identifiers for LHX2 Gene
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq, Jul 2008]
GeneCards Summary for LHX2 Gene
LHX2 (LIM Homeobox 2) is a Protein Coding gene. Diseases associated with LHX2 include Hyaline Fibromatosis Syndrome and Schizencephaly. Among its related pathways are Neural Crest Differentiation. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and obsolete transcription factor activity, RNA polymerase II transcription factor binding. An important paralog of this gene is LHX9.
UniProtKB/Swiss-Prot Summary for LHX2 Gene
Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).