Aliases for LHX1 Gene
External Ids for LHX1 Gene
Previous GeneCards Identifiers for LHX1 Gene
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor important for the development of the renal and urogenital systems. This gene is a candidate for Mayer-Rokitansky-Kuster-Hauser syndrome, a disorder characterized by anomalies in the female genital tract. [provided by RefSeq, Dec 2010]
GeneCards Summary for LHX1 Gene
LHX1 (LIM Homeobox 1) is a Protein Coding gene. Diseases associated with LHX1 include Chromosome 17Q12 Deletion Syndrome and Mayer-Rokitansky-Kuster-Hauser Syndrome. Among its related pathways are Ectoderm Differentiation and Neural Crest Differentiation. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and transcription corepressor activity. An important paralog of this gene is LHX5.
UniProtKB/Swiss-Prot for LHX1 Gene
Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis.