Aliases for LHCGR Gene
External Ids for LHCGR Gene
Previous HGNC Symbols for LHCGR Gene
Previous GeneCards Identifiers for LHCGR Gene
This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]
GeneCards Summary for LHCGR Gene
LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor) is a Protein Coding gene. Diseases associated with LHCGR include Precocious Puberty, Male-Limited and Leydig Cell Hypoplasia, Type I. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and luteinizing hormone receptor activity. An important paralog of this gene is FSHR.
UniProtKB/Swiss-Prot Summary for LHCGR Gene
Receptor for lutropin-choriogonadotropic hormone (PubMed:11847099). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099).