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This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and o... See more...
Aliases for LHB Gene
Aliases for LHB Gene
External Ids for LHB Gene
- HGNC: 6584
- Entrez Gene: 3972
- Ensembl: ENSG00000104826
- OMIM: 152780
- UniProtKB: P01229
Previous GeneCards Identifiers for LHB Gene
- GC19M050177
- GC19M049887
- GC19M054195
- GC19M054211
- GC19M049519
- GC19M045895
Summaries for LHB Gene
-
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008]
GeneCards Summary for LHB Gene
LHB (Luteinizing Hormone Subunit Beta) is a Protein Coding gene. Diseases associated with LHB include Hypogonadotropic Hypogonadism 23 Without Anosmia and Hypogonadism. Among its related pathways are Integrin Pathway and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and hormone activity. An important paralog of this gene is CGB3.
UniProtKB/Swiss-Prot Summary for LHB Gene
-
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
Additional gene information for LHB Gene
- HGNC(6584)
- Entrez Gene(3972)
- Ensembl(ENSG00000104826)
- OMIM(152780)
- UniProtKB(P01229)
- Open Targets Platform(ENSG00000104826)
- Monarch Initiative
- Search for LHB at DataMed
- Search for LHB at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LHB Gene
Genomics for LHB Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for LHB Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around LHB on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for LHB
- Top Transcription factor binding sites by QIAGEN in the LHB gene promoter:
-
- AhR
- Egr-3
- GATA-1
- NF-1
- NF-1/L
- Pax-5
- RREB-1
Genomic Locations for LHB Gene
Genomic Locations for LHB Gene
- chr19:49,015,980-49,017,091
- (GRCh38/hg38)
- Size:
- 1,112 bases
- Orientation:
- Minus strand
- chr19:49,519,237-49,520,347
- (GRCh37/hg19)
- Size:
- 1,111 bases
- Orientation:
- Minus strand
Genomic View for LHB Gene
Genes around LHB on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by HGNC
- 19q13.33 by Entrez Gene
- 19q13.33 by Ensembl
LHB Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LHB Gene
Proteins for LHB Gene
-
Protein details for LHB Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P01229-LSHB_HUMAN
- Recommended name:
- Lutropin subunit beta
- Protein Accession:
- P01229
- Q9UDI0
Protein attributes for LHB Gene
- Size:
- 141 amino acids
- Molecular mass:
- 15345 Da
- Quaternary structure:
-
- Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
Post-translational modifications for LHB Gene
Other Protein References for LHB Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ LHB Antibody
- RayBiotech Rabbit Anti-Human LH
- NSJ Bioreagents LHB Antibody (Mouse Monoclonal)
- Novus Biologicals Antibodies for LHB
-
Abcam antibodies for LHB
- Invitrogen Antibodies for LHB (AFLGC-LHB)
- antibodies-online: Show 93 available LHB Antibodies ranked by validation data
- Compare Top LHB Antibodies
-
Recommended
- 43 WB Antibodies (anti-human)
- 33 IHC (p) Antibodies (anti-human)
- 21 IHC (f) Antibodies (anti-human)
- 8 EIA Antibodies (anti-human)
- 5 IHC Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 1 Con Antibody (anti-human)
- 1 D Antibody (anti-human)
- 1 PrA Antibody (anti-human)
- 1 RIA Antibody (anti-human)
- 7 WB Antibodies (anti-mouse)
- 12 WB Antibodies (anti-rat)
-
Santa Cruz Biotechnology (SCBT) Antibodies for LHB
Protein Products
- RayBiotech Recombinant Human Lutropin subunit beta
- Search Origene for MassSpec and Protein Over-expression Lysates for LHB
- Origene Custom Protein Services for LHB
- Novus Biologicals lysates for LHB
- antibodies-online: Show 25 available LHB Proteins ranked by validation data
- Compare Top LHB Proteins
-
Signalway Proteins for LHB
Assay Products
- G Biosciences Immunotag™ Lutropin subunit beta ELISA Kit
- Novus Biologicals ELISA Kits for LHB
-
Signalway ELISA kits for LHB
No data available for DME Specific Peptides for LHB Gene
Domains & Families for LHB Gene
Gene Families for LHB Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Disease related genes
- Predicted secreted proteins
Protein Domains for LHB Gene
- InterPro:
- Blocks:
-
- Growth factor cystine knot superfamily signature
- Cystine knot domain
- Gonadotropin, beta chain
- ProtoNet:
Suggested Antigen Peptide Sequences for LHB Gene
- GenScript: Design optimal peptide antigens:
-
- Luteinizing hormone beta subunit (A7Y161_HUMAN)
- Luteinizing hormone subunit beta (LSHB_HUMAN)
- Luteinizing hormone beta subunit (Q8WXL0_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P01229- Family:
-
- Belongs to the glycoprotein hormones subunit beta family.
Function for LHB Gene
Molecular function for LHB Gene
- UniProtKB/Swiss-Prot Function:
- Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
- GENATLAS Biochemistry:
- luteinizing hormone,beta polypeptide (see CGB@),whith a common genetic variant-leading in the heterozygous or homozygous type to slight but significant alterations in ovarian steroido genesis,delayed progression of puberty in males
Phenotypes From GWAS Catalog for LHB Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | signaling receptor binding | TAS | 10484773 |
| GO:0005179 | contributes_to hormone activity | IBA | 21873635 |
Phenotypes for LHB Gene
- MGI mutant phenotypes for LHB:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for LHB:
Animal Models for LHB Gene
- MGI Knock Outs for LHB:
-
- Lhb Lhb<tm1Kmr>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LHB - Select products 50% OFF >
- * LHB CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for LHB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LHB
-
Santa Cruz Biotechnology (SCBT) CRISPR for LHB
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LHB
- Browse OriGene Inhibitory RNA Products For LHB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LHB
Clone Products
- Applied Biological Materials (abm): Clones for LHB - Select products 50% OFF >
- * LHB as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for LHB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LHB
Cell Line Products
-
Horizon Cell Lines for LHB
No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for LHB Gene
Localization for LHB Gene
Subcellular locations from UniProtKB/Swiss-Prot for LHB Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| golgi apparatus | 4 |
| nucleus | 3 |
| plasma membrane | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005737 | cytoplasm | IBA | 21873635 |
| GO:0005796 | Golgi lumen | TAS | -- |
Pathways & Interactions for LHB Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Apoptotic Pathways in Synovial Fibroblasts |
Cellular Apoptosis Pathway
.85
Mitochondrial Apoptosis
.85
Apoptotic Pathways in Synovial Fibroblasts
.84
p53 Mediated Apoptosis
.84
DHA Signaling
.74
Telomerase Components in Cell Signaling
.72
PPAR Pathway
.66
|
Rac1 Pathway
.65
Glioma Invasiveness
.64
Actin-Based Motility by Rho Family GTPases
.62
ERK5 Signaling
.61
eIF2 Pathway
.60
Rap1 Pathway
.57
Nuclear Receptor Activation by Vitamin-A
.57
|
| 2 | GPCR Pathway |
Paxillin Interactions
.73
Ras Pathway
.73
GPCR Pathway
.62
Pancreatic Adenocarcinoma
.59
|
Breast Cancer Regulation by Stathmin1
.58
NFAT in Immune Response
.58
Estrogen Pathway
.55
|
| 3 | ERK Signaling |
ERK Signaling
.61
Rho Family GTPases
.61
MAPK Signaling
.58
|
Molecular Mechanisms of Cancer
.51
ILK Signaling
.49
|
| 4 | Nanog in Mammalian ESC Pluripotency |
GSK3 Signaling
.62
Nanog in Mammalian ESC Pluripotency
.62
|
14-3-3 Induced Intracellular Signaling
.59
eNOS Signaling
.48
|
| 5 | CREB Pathway |
CREB Pathway
.68
IP3 Pathway
.68
|
Activation of PKC through GPCR
.63
Intracellular Calcium Signaling
.50
|
Pathways by source for LHB Gene
1 BioSystems pathway for LHB Gene
21 Reactome pathways for LHB Gene
6 KEGG pathways for LHB Gene
1 GeneGo (Thomson Reuters) pathway for LHB Gene
- Development Role of Activin A in cell differentiation and proliferation
55 Qiagen pathways for LHB Gene
- 14-3-3 Induced Intracellular Signaling
- Actin-Based Motility by Rho Family GTPases
- Activation of cAMP-Dependent PKA
- Activation of PKA through GPCR
- Activation of PKC through GPCR
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006701 | progesterone biosynthetic process | TAS | 14557487 |
| GO:0007165 | signal transduction | TAS | 10484773 |
| GO:0007186 | G protein-coupled receptor signaling pathway | TAS | -- |
| GO:0007267 | cell-cell signaling | TAS | 10484773 |
| GO:0008584 | male gonad development | TAS | 6785294 |
Drugs & Compounds for LHB Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
- RayBiotech Recombinant Human Lutropin subunit beta
Transcripts for LHB Gene
mRNA/cDNA for LHB Gene
- 1 REFSEQ mRNAs :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000649238 524 nts (view in UCSC)
- ENST00000649284 510 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LHB - Select products 50% OFF >
- * LHB CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for LHB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LHB
-
Santa Cruz Biotechnology (SCBT) CRISPR for LHB
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LHB
- Browse OriGene Inhibitory RNA Products For LHB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LHB
Clone Products
- Applied Biological Materials (abm): Clones for LHB - Select products 50% OFF >
- * LHB as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for LHB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LHB
Relevant External Links for LHB Gene
- GeneLoc Exon Structure for
- LHB
Expression for LHB Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
- Brain (Nervous System)
mRNA differential expression in normal tissues according to GTEx for LHB Gene
This gene is overexpressed in Pituitary (x52.1).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LHB
SOURCE GeneReport for Unigene cluster for LHB Gene:
Hs.154704mRNA Expression by UniProt/SwissProt for LHB Gene:
P01229-LSHB_HUMAN
Tissue specificity:
Pituitary gland.
Evidence on tissue expression from TISSUES for LHB Gene
- Nervous system(4.6)
- Kidney(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for LHB Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- endocrine
- integumentary
- nervous
- reproductive
Regions:
Head and neck:
- brain
- head
- pituitary gland
Thorax:
- breast
Pelvis:
- ovary
- penis
- prostate
- testicle
- uterus
- vagina
- vulva
General:
- hair
- skin
Primer Products
-
OriGene qPCR primer pairs for LHB
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for LHB Gene
Orthologs for LHB Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LHB 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | LHB 30 31 |
|
OneToMany | |
| Dog (Canis familiaris) |
Mammalia | LHB 30 31 |
|
OneToMany | |
| Rat (Rattus norvegicus) |
Mammalia | Lhb 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Lhb 30 17 31 |
|
OneToMany | |
| Oppossum (Monodelphis domestica) |
Mammalia | LHB 31 |
|
OneToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100490615 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | lhb 30 31 |
|
OneToMany |
- Species where no ortholog for LHB was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for LHB Gene
- ENSEMBL:
- Gene Tree for LHB (if available)
- TreeFam:
- Gene Tree for LHB (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LHB: view image
Paralogs for LHB Gene
Variants for LHB Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LHB Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 714891 | Benign: not provided | 49,016,305(-) | G/C | SYNONYMOUS_VARIANT | |
| 721564 | Likely Benign: not provided | 49,016,232(-) | G/A | MISSENSE_VARIANT | |
| 759653 | Likely Benign: not provided | 49,016,284(-) | C/T | SYNONYMOUS_VARIANT | |
| 769028 | Benign: not provided | 49,016,261(-) | G/T | MISSENSE_VARIANT | |
| 769029 | Benign: not provided | 49,017,058(-) | T/C | INTRON_VARIANT |
Residual Variation Intolerance Score:
87.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.37;
53.95% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LHB Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LHB Gene
Disorders for LHB Gene
(10) MalaCards diseases for LHB Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hypogonadotropic hypogonadism 23 without anosmia |
|
|
| hypogonadism |
|
|
| amenorrhea |
|
|
| infertility |
|
|
| hypogonadotropic hypogonadism |
|
|
Search LHB in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
LSHB_HUMAN- Hypogonadotropic hypogonadism 23 without anosmia (HH23) [MIM:228300]: A form of hypogonadotropic hypogonadism, a group of disorders characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. HH23 male patients have normal sexual differentiation, reduced or absent Leydig cells, reduced or absent spermatogenesis, and absence of spontaneous puberty. Female patients exhibit normal pubertal development and menarche, followed by oligomenorrhea and anovulatory secondary amenorrhea. {ECO:0000269 PubMed:1727547}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Genatlas disease for LHB Gene
fertile eunuchoidism,hypogonadotropic hypogonadism,male infantilism,male infertility in heterozygotes but normal sexual development and fertility in female heterozygotes
Additional Disease Information for LHB
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
Publications for LHB Gene
- Human pituitary lutropin. Isolation, properties, and the complete amino acid sequence of the beta-subunit. (PMID: 1191677) Sairam MR … Li CH (Biochimica et biophysica acta 1975) 2 3 4
- A large-scale candidate gene association study of age at menarche and age at natural menopause. (PMID: 20734064) He C … Hunter DJ (Human genetics 2010) 3 41
- Luteinizing hormone beta-subunit gene (LHbeta) polymorphism in infertility and endometriosis-associated infertility. (PMID: 20430510) Mafra FA … Barbosa CP (European journal of obstetrics, gynecology, and reproductive biology 2010) 3 41
- High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PMID: 19453261) Yerges LM … MrOS Research Group (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009) 3 41
- Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3). (PMID: 19574343) Ahn J … Hayes RB (Human molecular genetics 2009) 3 41
ExternalLinks
Products for LHB Gene
- Custom Antibody ServicesOriGene Antibodies for LHB
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for LHB
- Origene Custom Protein Services for LHB
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LHB
- Browse OriGene Inhibitory RNA Products For LHB
- OriGene qPCR primer pairs for LHB
- OriGene CRISPR knockouts for LHB
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For LHB
- Sino Biological Human cDNA Clone for LHB
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for LHB
- Novus Biologicals lysates for LHB
- Novus Biologicals ELISA Kits for LHB
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for LHB
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for LHB (AFLGC-LHB)
- VectorBuilder Custom and pre-made DNA vectors for LHB (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for LHB (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for LHB (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for LHB CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for LHB
- antibodies-online: Show 93 available LHB Antibodies ranked by validation data
- Compare Top LHB Antibodies
- Recommended
- 43 WB Antibodies (anti-human)
- 33 IHC (p) Antibodies (anti-human)
- 21 IHC (f) Antibodies (anti-human)
- 8 EIA Antibodies (anti-human)
- 5 IHC Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 1 Con Antibody (anti-human)
- 1 D Antibody (anti-human)
- 1 PrA Antibody (anti-human)
- 1 RIA Antibody (anti-human)
- 7 WB Antibodies (anti-mouse)
- 12 WB Antibodies (anti-rat)
- antibodies-online: Show 25 available LHB Elisa Kits ranked by validation data
- Compare Top LHB Elisa Kits
- antibodies-online: Show 25 available LHB Proteins ranked by validation data
- Compare Top LHB Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for LHB
- Search Santa Cruz Biotechnology (SCBT) for LHB siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for LHB
- Horizon Cell Lines for LHB
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LHB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LHB
- Search GeneCopoeia for miRNA 3'UTR Target clone products for LHB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LHB
Sources for LHB Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB