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Aliases for LGI3 Gene
Aliases for LGI3 Gene
External Ids for LGI3 Gene
- HGNC: 18711
- Entrez Gene: 203190
- Ensembl: ENSG00000168481
- OMIM: 608302
- UniProtKB: Q8N145
Previous GeneCards Identifiers for LGI3 Gene
- GC08M021762
- GC08M022356
- GC08M021824
- GC08M022026
- GC08M022060
- GC08M020546
Summaries for LGI3 Gene
GeneCards Summary for LGI3 Gene
LGI3 (Leucine Rich Repeat LGI Family Member 3) is a Protein Coding gene. Diseases associated with LGI3 include Epilepsy, Familial Temporal Lobe, 3 and Epilepsy, Familial Temporal Lobe, 1. Among its related pathways are LGI-ADAM interactions and Developmental Biology. An important paralog of this gene is LGI1.
UniProtKB/Swiss-Prot Summary for LGI3 Gene
-
May participate in the regulation of neuronal exocytosis.
Additional gene information for LGI3 Gene
- HGNC(18711)
- Entrez Gene(203190)
- Ensembl(ENSG00000168481)
- OMIM(608302)
- UniProtKB(Q8N145)
- Open Targets Platform(ENSG00000168481)
- Search for LGI3 at DataMed
- Search for LGI3 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LGI3 Gene
Genomics for LGI3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for LGI3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around LGI3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for LGI3
- Top Transcription factor binding sites by QIAGEN in the LGI3 gene promoter:
-
- GR
- GR-alpha
- GR-beta
- p53
Genomic Locations for LGI3 Gene
Genomic Locations for LGI3 Gene
- chr8:22,146,830-22,157,084
- (GRCh38/hg38)
- Size:
- 10,255 bases
- Orientation:
- Minus strand
- chr8:22,004,338-22,014,597
- (GRCh37/hg19)
- Size:
- 10,260 bases
- Orientation:
- Minus strand
Genomic View for LGI3 Gene
Genes around LGI3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p21.3 by HGNC
- 8p21.3 by Entrez Gene
- 8p21.3 by Ensembl
LGI3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LGI3 Gene
Proteins for LGI3 Gene
-
Protein details for LGI3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N145-LGI3_HUMAN
- Recommended name:
- Leucine-rich repeat LGI family member 3
- Protein Accession:
- Q8N145
- A5PLP2
- Q86TL4
- Q8N296
Protein attributes for LGI3 Gene
- Size:
- 548 amino acids
- Molecular mass:
- 61704 Da
- Quaternary structure:
-
- Interacts with STX1A.
- SequenceCaution:
-
- Sequence=BAC03553.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for LGI3 Gene
Post-translational modifications for LGI3 Gene
Other Protein References for LGI3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-LGI3 (aa 449-548) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for LGI3
- Novus Biologicals Antibodies for LGI3
-
Abcam antibodies for LGI3
- Invitrogen Antibodies for LGI3 (AFLGC-Lgi3)
-
Boster Bio Antibodies for LGI3
-
Custom Antibody ServicesProSci Antibodies for LGI3
Protein Products
-
OriGene Purified Proteins for LGI3
- Search Origene for MassSpec and Protein Over-expression Lysates for LGI3
- Origene Custom Protein Services for LGI3
- antibodies-online: Show 6 available LGI3 Proteins ranked by validation data
- Compare Top LGI3 Proteins
-
Quality Products:
-
Abcam proteins for LGI3
Assay Products
- antibodies-online: Show 12 available LGI3 Elisa Kits ranked by validation data
- Compare Top LGI3 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for LGI3 Gene
Domains & Families for LGI3 Gene
Gene Families for LGI3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for LGI3 Gene
- InterPro:
- Blocks:
-
- Cysteine-rich flanking region, C-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for LGI3 Gene
- GenScript: Design optimal peptide antigens:
-
- Leucine-rich glioma-inactivated protein 3 (LGI3_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LGI3 Gene
Function for LGI3 Gene
Molecular function for LGI3 Gene
- UniProtKB/Swiss-Prot Function:
- May participate in the regulation of neuronal exocytosis.
Phenotypes From GWAS Catalog for LGI3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003824 | catalytic activity | IEA | -- |
| GO:0005515 | protein binding | IEA | -- |
Phenotypes for LGI3 Gene
- MGI mutant phenotypes for LGI3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for LGI3:
Animal Model Products
-
Taconic Biosciences Mouse Models for LGI3
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LGI3 - Select products 50% OFF >
- * LGI3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for LGI3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LGI3
-
Santa Cruz Biotechnology (SCBT) CRISPR for LGI3
miRNA for LGI3 Gene
- miRTarBase miRNAs that target LGI3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LGI3
- Browse OriGene Inhibitory RNA Products For LGI3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LGI3
Clone Products
- Applied Biological Materials (abm): Clones for LGI3 - Select products 50% OFF >
- * LGI3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for LGI3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LGI3
Cell Line Products
-
Horizon Cell Lines for LGI3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for LGI3 Gene
Localization for LGI3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for LGI3 Gene
- Secreted. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Cell junction, synapse, synaptosome. Note=Found in the synaptosomal membrane fraction. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| cytosol | 3 |
| plasma membrane | 2 |
| cytoskeleton | 1 |
| nucleus | 1 |
| endosome | 1 |
| mitochondrion | 0 |
| peroxisome | 0 |
| endoplasmic reticulum | 0 |
| lysosome | 0 |
| golgi apparatus | 0 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0008021 | synaptic vesicle | IEA | -- |
| GO:0030054 | cell junction | IEA | -- |
| GO:0031410 | cytoplasmic vesicle | IEA | -- |
| GO:0043005 | neuron projection | IEA | -- |
Pathways & Interactions for LGI3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Developmental Biology | ||
| 2 | LGI-ADAM interactions | ||
Pathways by source for LGI3 Gene
2 Reactome pathways for LGI3 Gene
Interacting Proteins for LGI3 Gene
GPS-Prot Interaction Network for LGI3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006887 | exocytosis | IEA | -- |
| GO:0017157 | regulation of exocytosis | IEA | -- |
No data available for SIGNOR curated interactions for LGI3 Gene
Transcripts for LGI3 Gene
mRNA/cDNA for LGI3 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000306317 3241 nts (view in UCSC)
- ENST00000424267 3114 nts (view in UCSC)
- ENST00000517694 663 nts (view in UCSC)
- ENST00000518365 784 nts (view in UCSC)
- ENST00000520124 4420 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LGI3 - Select products 50% OFF >
- * LGI3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for LGI3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LGI3
-
Santa Cruz Biotechnology (SCBT) CRISPR for LGI3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LGI3
- Browse OriGene Inhibitory RNA Products For LGI3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LGI3
Clone Products
- Applied Biological Materials (abm): Clones for LGI3 - Select products 50% OFF >
- * LGI3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for LGI3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LGI3
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||
| SP2: | |||||||||||||||||||
| SP3: |
Relevant External Links for LGI3 Gene
- GeneLoc Exon Structure for
- LGI3
Expression for LGI3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Eye (Sensory Organs)
- Cholinergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- Cholinergic Amacrine Cells Inner Nuclear Layer
-
Limb (Muscoskeletal System)
- Limb Muscle Progenitor Cells Forelimb Myotome
-
Skeletal Muscle (Muscoskeletal System)
- Limb Muscle Progenitor Cells Forelimb Myotome
-
Lung (Respiratory System)
mRNA differential expression in normal tissues according to GTEx for LGI3 Gene
This gene is overexpressed in Brain - Cortex (x5.6), Brain - Spinal cord (cervical c-1) (x5.4), Brain - Frontal Cortex (BA9) (x5.0), Brain - Substantia nigra (x4.8), and Brain - Putamen (basal ganglia) (x4.8).
This gene is overexpressed in Frontal cortex (51.3) and Spinal cord (16.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for LGI3 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LGI3
SOURCE GeneReport for Unigene cluster for LGI3 Gene:
Hs.33470mRNA Expression by UniProt/SwissProt for LGI3 Gene:
Q8N145-LGI3_HUMAN
Tissue specificity:
Widely expressed, with highest levels in brain and lung.
Evidence on tissue expression from TISSUES for LGI3 Gene
- Nervous system(4.7)
Primer Products
-
OriGene qPCR primer pairs for LGI3
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for LGI3 Gene
Orthologs for LGI3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LGI3 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | LGI3 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | LGI3 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Lgi3 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Lgi3 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | LGI3 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | LGI3 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | lgi3 30 31 |
|
OneToOne |
- Species where no ortholog for LGI3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for LGI3 Gene
- ENSEMBL:
- Gene Tree for LGI3 (if available)
- TreeFam:
- Gene Tree for LGI3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LGI3: view image
Paralogs for LGI3 Gene
Paralogs for LGI3 Gene
(5) SIMAP similar genes for LGI3 Gene using alignment to 4 proteins:
- LGI3_HUMAN
- A5PLP2_HUMAN
- E5RIV5_HUMAN
- H0YAP4_HUMAN
Variants for LGI3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LGI3 Gene
| SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 745609 | Likely Benign: not provided | 22,156,508(-) | G/A | MISSENSE_VARIANT | |
| 770570 | Benign: not provided | 22,148,657(-) | C/T | MISSENSE_VARIANT | |
| rs34112456 | - | p.Ala524Thr |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv12054n54 | CNV | loss | 21841781 |
| dgv12055n54 | CNV | loss | 21841781 |
| dgv2060e212 | CNV | loss | 25503493 |
| dgv881n27 | CNV | loss | 19166990 |
| esv2759604 | CNV | loss | 17122850 |
| esv3572630 | CNV | loss | 25503493 |
| nsv465613 | CNV | loss | 19166990 |
| nsv470204 | CNV | loss | 18288195 |
| nsv524720 | CNV | loss | 19592680 |
| nsv527293 | CNV | loss | 19592680 |
| nsv528590 | CNV | loss | 19592680 |
| nsv610765 | CNV | loss | 21841781 |
| nsv610771 | CNV | loss | 21841781 |
| nsv831263 | CNV | loss | 17160897 |
| nsv831264 | CNV | gain+loss | 17160897 |
Residual Variation Intolerance Score:
24.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.11;
61.14% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LGI3 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LGI3 Gene
Disorders for LGI3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| epilepsy, familial temporal lobe, 3 |
|
|
| epilepsy, familial temporal lobe, 1 |
|
|
| benign familial infantile epilepsy |
|
|
Search LGI3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for LGI3
No data available for UniProtKB/Swiss-Prot and Genatlas for LGI3 Gene
Publications for LGI3 Gene
- The LGI1 gene involved in lateral temporal lobe epilepsy belongs to a new subfamily of leucine-rich repeat proteins. (PMID: 12023020) Gu W … Steinlein OK (FEBS letters 2002) 2 3 4 23
- Leucine-rich glioma inactivated 3 is involved in amyloid beta peptide uptake by astrocytes and endocytosis itself. (PMID: 18628660) Okabayashi S … Kimura N (Neuroreport 2008) 2 3
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4
ExternalLinks
Products for LGI3 Gene
- Custom Antibody ServicesOriGene Antibodies for LGI3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for LGI3
- Search Origene for MassSpec and Protein Over-expression Lysates for LGI3
- Origene Custom Protein Services for LGI3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LGI3
- Browse OriGene Inhibitory RNA Products For LGI3
- OriGene qPCR primer pairs for LGI3
- OriGene CRISPR knockouts for LGI3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For LGI3
- Sino Biological Human cDNA Clone for LGI3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for LGI3
- Novus Biologicals proteins and lysates for LGI3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for LGI3
- Abcam proteins for LGI3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for LGI3
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for LGI3 (AFLGC-Lgi3)
- VectorBuilder Custom and pre-made DNA vectors for LGI3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for LGI3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for LGI3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for LGI3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for LGI3
- antibodies-online: Show 13 available LGI3 Antibodies ranked by validation data
- Compare Top LGI3 Antibodies
- antibodies-online: Show 12 available LGI3 Elisa Kits ranked by validation data
- Compare Top LGI3 Elisa Kits
- Quality Products:
- antibodies-online: Show 6 available LGI3 Proteins ranked by validation data
- Compare Top LGI3 Proteins
- Quality Products:
- Custom Antibody ServicesProSci Antibodies for LGI3
- Search for LGI3 Proteins at ProSci
- Horizon Cell Lines for LGI3
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LGI3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LGI3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for LGI3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LGI3
- Boster Bio Antibodies for LGI3
- Browse Boster Bio ELISA Kits
Sources for LGI3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB