Aliases for LGALS7 Gene
External Ids for LGALS7 Gene
Previous GeneCards Identifiers for LGALS7 Gene
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]
GeneCards Summary for LGALS7 Gene
LGALS7 (Galectin 7) is a Protein Coding gene. Diseases associated with LGALS7 include Gm1-Gangliosidosis, Type Ii and Gm1-Gangliosidosis, Type I. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is LGALS7B.
UniProtKB/Swiss-Prot for LGALS7 Gene
Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.