Aliases for LGALS7 Gene
External Ids for LGALS7 Gene
Previous GeneCards Identifiers for LGALS7 Gene
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008]
GeneCards Summary for LGALS7 Gene
LGALS7 (Galectin 7) is a Protein Coding gene. Diseases associated with LGALS7 include Postencephalitic Parkinson Disease and Neurodegeneration With Brain Iron Accumulation 2A. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is LGALS7B.
UniProtKB/Swiss-Prot for LGALS7 Gene
Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.