Aliases for LGALS1 Gene
Aliases for LGALS1 Gene
External Ids for LGALS1 Gene
- HGNC: 6561
- Entrez Gene: 3956
- Ensembl: ENSG00000100097
- OMIM: 150570
- UniProtKB: P09382
Previous GeneCards Identifiers for LGALS1 Gene
- GC22P034686
- GC22P036314
- GC22P036396
- GC22P038071
- GC22P021039
Summaries for LGALS1 Gene
-
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq, Jul 2008]
GeneCards Summary for LGALS1 Gene
LGALS1 (Galectin 1) is a Protein Coding gene. Diseases associated with LGALS1 include Benign Metastasizing Leiomyoma and Thyroid Cancer. Among its related pathways are Apoptosis and Autophagy and MAP Kinase Signaling. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity. An important paralog of this gene is LGALS2.
UniProtKB/Swiss-Prot for LGALS1 Gene
-
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Additional gene information for LGALS1 Gene
- Monarch Initiative
- Search for LGALS1 at DataMed
- Search for LGALS1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LGALS1 Gene
Genomics for LGALS1 Gene
GeneHancer (GH) Regulatory Elements for LGALS1 Gene
Promoters and enhancers for LGALS1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around LGALS1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the LGALS1 gene promoter:
-
- AP-1
- p53
- c-Jun
- ATF-2
- YY1
- HEN1
- MyoD
- E2F-1
- E2F
Regulatory Element Products
Genomic Locations for LGALS1 Gene
Genomic Locations for LGALS1 Gene
- chr22:37,675,606-37,679,806
- (GRCh38/hg38)
- Size:
- 4,201 bases
- Orientation:
- Plus strand
- chr22:38,071,613-38,075,813
- (GRCh37/hg19)
- Size:
- 4,201 bases
- Orientation:
- Plus strand
Genomic View for LGALS1 Gene
Genes around LGALS1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q13.1 by Entrez Gene
- 22q13.1 by HGNC
- 22q13.1 by Ensembl
LGALS1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LGALS1 Gene
Proteins for LGALS1 Gene
-
Protein details for LGALS1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P09382-LEG1_HUMAN
- Recommended name:
- Galectin-1
- Protein Accession:
- P09382
- B2R5E8
- Q9UDK5
Protein attributes for LGALS1 Gene
- Size:
- 135 amino acids
- Molecular mass:
- 14716 Da
- Quaternary structure:
-
- Homodimer. Binds LGALS3BP. Interacts with CD2, CD3, CD4, CD6, CD7, CD43, ALCAM and CD45. Interacts with laminin (via poly-N-acetyllactosamine). Interacts with SUSD2.
Protein Expression for LGALS1 Gene
Post-translational modifications for LGALS1 Gene
Other Protein References for LGALS1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for LGALS1 (Galectin-1)
-
Custom Antibody ServicesOriGene Antibodies for LGALS1
- Novus Biologicals Antibodies for LGALS1
-
Abcam antibodies for LGALS1
- Invitrogen Antibodies for LGALS1 (AFLGC-LGALS1)
- antibodies-online: Search results for 271 available LGALS1 Antibodies ranked by validation data
- Compare Top LGALS1 Antibodies
-
Recommended
- 78 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 1 FACS Antibody (anti-mouse)
- 1 IHC (fro) Antibody (anti-mouse)
- 153 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 5 RIA Antibodies (anti-human)
- 4 FACS Antibodies (anti-human)
- 3 IHC Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-human)
- 1 CC Antibody (anti-human)
- 59 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- GeneTex LGALS1 Antibody for LGALS1
-
Santa Cruz Biotechnology (SCBT) Antibodies for LGALS1
- Sino Biological Antibodies for LGALS1
Protein Products
- R&D Systems Proteins and Enzymes for LGALS1 (Galectin-1)
- Search Origene for MassSpec and Protein Over-expression Lysates for LGALS1
- Origene Custom Protein Services for LGALS1
- Sino Biological Recombinant Proteins for LGALS1
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for LGALS1
- GeneTex Proteins for LGALS1
-
ProSci Proteins for LGALS1
-
Abcam proteins for LGALS1
Assay Products
- R&D Systems ELISAs, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for LGALS1 (Galectin-1)
- Novus Biologicals ELISA Kits for LGALS1
- antibodies-online: Search results for 69 available LGALS1 Elisa Kits ranked by validation data
- Compare Top LGALS1 Elisa Kits
-
Recommended
- 1 Chicken ELISA Kit
- 6 Cow (Bovine) ELISA Kits
- 1 Dog (Canine) ELISA Kit
- 2 Goat ELISA Kits
- 2 Guinea Pig ELISA Kits
- 16 Human ELISA Kits
- 2 Monkey ELISA Kits
- 20 Mouse (Murine) ELISA Kits
- 5 Pig (Porcine) ELISA Kits
- 2 Rabbit ELISA Kits
- 10 Rat (Rattus) ELISA Kits
- 1 Rhesus Monkey ELISA Kit
- 1 Sheep (Ovine) ELISA Kit
- 1 Wild boar (Sus scrofa) ELISA Kit
-
Abcam assays for LGALS1
- Sino Biological Assays for LGALS1
No data available for DME Specific Peptides for LGALS1 Gene
Domains & Families for LGALS1 Gene
Gene Families for LGALS1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for LGALS1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for LGALS1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for LGALS1 Gene
Function for LGALS1 Gene
Molecular function for LGALS1 Gene
- UniProtKB/Swiss-Prot Function:
- Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
- GENATLAS Biochemistry:
- lectin,galactoside-beta binding,soluble 1,autocrine negative growth factor (L14-I)
Phenotypes From GWAS Catalog for LGALS1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | HDA | 22658674 |
| GO:0004871 | obsolete signal transducer activity | HMP | -- |
| GO:0005515 | protein binding | IPI | 10369126 |
| GO:0030246 | carbohydrate binding | IEA | -- |
| GO:0030395 | lactose binding | IEA | -- |
Phenotypes for LGALS1 Gene
- MGI mutant phenotypes for LGALS1:
-
inferred from 1 alleles
- respiratory system phenotype
- homeostasis/metabolism phenotype
- nervous system phenotype
- behavior/neurological phenotype
- integument phenotype
- taste/olfaction phenotype
- mortality/aging
- muscle phenotype
- craniofacial phenotype
- reproductive system phenotype
- immune system phenotype
- growth/size/body region phenotype
- GenomeRNAi human phenotypes for LGALS1:
Animal Models for LGALS1 Gene
- MGI Knock Outs for LGALS1:
-
- Lgals1 Lgals1<tm1Rob>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for LGALS1
-
CRISPR Products
-
OriGene CRISPR knockouts for LGALS1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LGALS1
- genomics-online: gRNA clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
- Applied Biological Materials CRISPR for LGALS1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for LGALS1
- GenScript: Design CRISPR guide RNA sequences for LGALS1
miRNA for LGALS1 Gene
- miRTarBase miRNAs that target LGALS1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LGALS1
- Browse OriGene Inhibitory RNA Products For LGALS1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LGALS1
- genomics-online: shRNA clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
Clone Products
- GenScript: Custom all cDNA clones Services for LGALS1
- Sino Biological Human cDNA Clone for LGALS1
- Addgene plasmids for LGALS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LGALS1
- Applied Biological Materials Clones for LGALS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for LGALS1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for LGALS1 Gene
Localization for LGALS1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for LGALS1 Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endoplasmic reticulum | 5 |
| cytosol | 5 |
| nucleus | 4 |
| plasma membrane | 3 |
| cytoskeleton | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IDA | 27068509 |
| GO:0005615 | extracellular space | HDA,IEA | 20551380 |
| GO:0005622 | intracellular | IDA | -- |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IEA,TAS | 16130169 |
Pathways & Interactions for LGALS1 Gene
Pathways by source for LGALS1 Gene
1 BioSystems pathway for LGALS1 Gene
3 Cell Signaling Technology pathways for LGALS1 Gene
Interacting Proteins for LGALS1 Gene
Selected Interacting proteins:
P09382-LEG1_HUMAN
ENSP00000215909
for LGALS1 Gene via
UniProtKB
STRING
IID
MINT
GPS-Prot Interaction Network for LGALS1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002317 | plasma cell differentiation | IEA | -- |
| GO:0006915 | apoptotic process | IEA,TAS | -- |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0010812 | negative regulation of cell-substrate adhesion | IEA | -- |
| GO:0010977 | negative regulation of neuron projection development | IEA | -- |
No data available for SIGNOR curated interactions for LGALS1 Gene
Drugs & Compounds for LGALS1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Dihydroartemisinin | Approved, Investigational | Pharma | Target, ligand | 100 | ||
| Thiodigalactoside | Experimental | Pharma | Target | 0 | ||
| 1,4-Dithiothreitol | Experimental | Pharma | Target | 0 | ||
| Beta-Mercaptoethanol | Experimental | Pharma | Target | 0 | ||
| mannose | Investigational | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
Transcripts for LGALS1 Gene
mRNA/cDNA for LGALS1 Gene
- (1) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (1106) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000472321 546 bps (uc062dzt.1)
- ENST00000489315 516 bps (uc062dzs.1)
- ENST00000454173 331 bps (uc062dzr.1)
- ENST00000480207 185 bps (uc062dzq.1)
- ENST00000425542 637 bps (uc062dzp.1)
Unigene Clusters for LGALS1 Gene
- Lectin, galactoside-binding, soluble, 1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for LGALS1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LGALS1
- genomics-online: gRNA clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
- Applied Biological Materials CRISPR for LGALS1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for LGALS1
- GenScript: Design CRISPR guide RNA sequences for LGALS1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LGALS1
- Browse OriGene Inhibitory RNA Products For LGALS1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LGALS1
- genomics-online: shRNA clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
Clone Products
- GenScript: Custom all cDNA clones Services for LGALS1
- Sino Biological Human cDNA Clone for LGALS1
- Addgene plasmids for LGALS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LGALS1
- Applied Biological Materials Clones for LGALS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||
| SP6: |
Expression for LGALS1 Gene
This gene is overexpressed in Amniocyte (9.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for LGALS1 Gene
NURSA nuclear receptor signaling pathways regulating expression of LGALS1 Gene:
LGALS1SOURCE GeneReport for Unigene cluster for LGALS1 Gene:
Hs.445351mRNA Expression by UniProt/SwissProt for LGALS1 Gene:
P09382-LEG1_HUMAN
Tissue specificity:
Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
Evidence on tissue expression from TISSUES for LGALS1 Gene
- Lung(4.9)
- Skin(4.9)
- Nervous system(4.9)
- Blood(4.6)
- Liver(4.6)
- Spleen(4.5)
- Muscle(3.4)
- Heart(3.2)
- Eye(3.1)
- Kidney(2.9)
- Intestine(2.8)
- Adrenal gland(2.5)
- Gall bladder(2.4)
- Stomach(2.4)
- Thyroid gland(2.3)
- Lymph node(2.2)
- Pancreas(2.1)
- Bone marrow(2)
Primer Products
-
OriGene qPCR primer pairs for LGALS1
-
OriGene qPCR primer pairs and template standards for LGALS1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for LGALS1 Gene
Orthologs for LGALS1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LGALS1 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | LGALS1 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | LGALS1 34 33 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| rat (Rattus norvegicus) |
Mammalia | Lgals1 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Lgals1 16 34 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | LGALS1 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | LGALS1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LGALS1 34 34 33 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100485378 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | lgals2b 34 33 |
|
OneToMany | |
| lgals2a 34 |
|
OneToMany | |||
| lgals1l1 34 |
|
OneToMany |
- Species where no ortholog for LGALS1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for LGALS1 Gene
- ENSEMBL:
- Gene Tree for LGALS1 (if available)
- TreeFam:
- Gene Tree for LGALS1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LGALS1: view image
Paralogs for LGALS1 Gene
Variants for LGALS1 Gene
| SNP ID | Clin | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000146429 | -- | 37,678,740(+) | C/T | intron_variant | |
| rs1000530168 | -- | 37,674,210(+) | G/A | upstream_transcript_variant | |
| rs1000598049 | -- | 37,674,997(+) | G/A | upstream_transcript_variant | |
| rs1000983739 | -- | 37,674,703(+) | G/A/C | upstream_transcript_variant | |
| rs1000985750 | -- | 37,673,852(+) | C/G | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2662670 | CNV | deletion | 23128226 |
| esv2758838 | CNV | loss | 17122850 |
| nsv1057617 | CNV | gain | 25217958 |
| nsv471197 | CNV | loss | 18288195 |
| nsv528985 | CNV | loss | 19592680 |
| nsv829203 | CNV | loss | 20364138 |
| nsv834191 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
38.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.40;
8.88% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LGALS1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- LGALS1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LGALS1 Gene
Disorders for LGALS1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| benign metastasizing leiomyoma |
|
|
| thyroid cancer |
|
|
| chronic monocytic leukemia |
|
|
| gestational trophoblastic neoplasm |
|
|
| bladder urothelial carcinoma |
|
|
Search LGALS1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for LGALS1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for LGALS1 Gene
Publications for LGALS1 Gene
- Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal-fetal immune tolerance. (PMID: 18824694) Than NG … Wildman DE (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 4 22 58
- Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1. (PMID: 18796645) Nishi N … Nakamura T (Glycobiology 2008) 3 4 22 58
- Presentation of galectin-1 by extracellular matrix triggers T cell death. (PMID: 14617626) He J … Baum LG (The Journal of biological chemistry 2004) 3 4 22 58
- Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation. (PMID: 11146440) Tinari N … Liu FT (International journal of cancer 2001) 3 4 22 58
- Regulation of CD45-induced signaling by galectin-1 in Burkitt lymphoma B cells. (PMID: 10764829) Fouillit M … Caron M (Glycobiology 2000) 3 4 22 58
Products for LGALS1 Gene
- R&D Systems Antibodies for LGALS1 (Galectin-1)
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- Cyagen custom Knockout/knockin (KOKI) mouse models for LGALS1
- Addgene plasmids for LGALS1
- antibodies-online: Search results for 271 available LGALS1 Antibodies ranked by validation data
- Compare Top LGALS1 Antibodies
- Recommended
- 78 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 1 FACS Antibody (anti-mouse)
- 1 IHC (fro) Antibody (anti-mouse)
- 153 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 5 RIA Antibodies (anti-human)
- 4 FACS Antibodies (anti-human)
- 3 IHC Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-human)
- 1 CC Antibody (anti-human)
- 59 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- antibodies-online: Search results for 69 available LGALS1 Elisa Kits ranked by validation data
- Compare Top LGALS1 Elisa Kits
- Recommended
- 1 Chicken ELISA Kit
- 6 Cow (Bovine) ELISA Kits
- 1 Dog (Canine) ELISA Kit
- 2 Goat ELISA Kits
- 2 Guinea Pig ELISA Kits
- 16 Human ELISA Kits
- 2 Monkey ELISA Kits
- 20 Mouse (Murine) ELISA Kits
- 5 Pig (Porcine) ELISA Kits
- 2 Rabbit ELISA Kits
- 10 Rat (Rattus) ELISA Kits
- 1 Rhesus Monkey ELISA Kit
- 1 Sheep (Ovine) ELISA Kit
- 1 Wild boar (Sus scrofa) ELISA Kit
- antibodies-online: Search results for 53 available LGALS1 Proteins ranked by validation data
- Compare Top LGALS1 Proteins
- GeneTex LGALS1 Antibody for LGALS1
- GeneTex Proteins for LGALS1
- Santa Cruz Biotechnology (SCBT) Antibodies for LGALS1
- Search Santa Cruz Biotechnology (SCBT) for LGALS1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for LGALS1
- Horizon Cell Lines for LGALS1
- genomics-online: cdna clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
- orf clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
- genomics-online: gRNA clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
- genomics-online: primer clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
- genomics-online: shRNA clones - Search results for 145 available LGALS1 gene related products
- Overview of 145 available LGALS1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LGALS1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LGALS1
- GeneCopoeia miRNA 3'UTR Target clone products for LGALS1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LGALS1
Sources for LGALS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt