Free for academic non-profit institutions. Other users need a Commercial license
LEPROTL1 (Leptin Receptor Overlapping Transcript Like 1) is a Protein Coding gene. Diseases associated with LEPROTL1 include Rectum Adenocarcinoma. An important paralog of this gene is LEPROT.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 16189514 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005768 | endosome | IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway | IBA | 21873635 |
GO:2000009 | negative regulation of protein localization to cell surface | IBA | 21873635 |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | LEPROTL1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | LEPROTL1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | LEPROTL1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Leprotl1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Leprotl1 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | LEPROTL1 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | LEPROTL1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | LEPROTL1 30 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100486533 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.28972 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | zgc:92045 30 |
|
||
LEPROTL1 31 |
|
OneToOne | |||
wufb95c07 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP008693 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG30423 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | C30B5.2 30 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | VPS55 31 33 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
709877 | Benign: not provided | 30,131,945(+) | A/G | STOP_LOST,INTRON_VARIANT | |
734148 | Benign: not provided | 30,132,685(+) | C/T | MISSENSE_VARIANT,INTRON_VARIANT | |
742348 | Likely Benign: not provided | 30,132,423(+) | A/T | SYNONYMOUS_VARIANT,INTRON_VARIANT | |
784126 | Benign: not provided | 30,132,393(+) | G/A | SYNONYMOUS_VARIANT,INTRON_VARIANT |
Disorder | Aliases | PubMed IDs |
---|---|---|
rectum adenocarcinoma |
|
|