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LELP1 (Late Cornified Envelope Like Proline Rich 1) is a Protein Coding gene. Diseases associated with LELP1 include Skin Disease. Among its related pathways are Keratinization and Developmental Biology. An important paralog of this gene is LCE5A.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH01J153203 | Promoter | 0.3 | EPDnew | 600.7 | 0.0 | -19 | 0.1 | LELP1 HSALNG0007273 SPRR2G | ||
GH01J153231 | Enhancer | 0.8 | Ensembl ENCODE | 10.8 | +27.8 | 27776 | 6.4 | CTCF ZNF143 TRIM22 ESRRA NR2C1 NR2F1 NFIB ZNF654 HNF4A TBX21 | PRR9 LORICRIN LELP1 SMCP SPRR2G RPLP0P4 lnc-LOR-4 | |
GH01J153122 | Enhancer | 0.9 | ENCODE | 9.5 | -79.8 | -79830 | 2.5 | CREB1 PRDM10 ZHX2 FOXA1 LARP7 ZIC2 TCF12 IKZF2 POLR2A GTF2F1 | piR-50968-009 SPRR2C SPRR2G LELP1 SPRR2B SPRR2F | |
GH01J153094 | Promoter | 0.3 | EPDnew | 9.6 | -108.9 | -108885 | 0.1 | SPRR2E SPRR2B SPRR2C LELP1 SPRR2F | ||
GH01J153251 | Enhancer | 0.2 | Ensembl | 10 | +48.1 | 48071 | 0.6 | PRR9 LELP1 LORICRIN HSALNG0007276 lnc-LOR-4 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Keratinization |
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|
2 | Developmental Biology |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | LELP1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | LELP1 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Lelp1 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | LELP1 31 |
|
OneToOne |
Disorder | Aliases | PubMed IDs |
---|---|---|
skin disease |
|