Aliases for LECT2 Gene
External Ids for LECT2 Gene
Previous GeneCards Identifiers for LECT2 Gene
This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]
GeneCards Summary for LECT2 Gene
LECT2 (Leukocyte Cell Derived Chemotaxin 2) is a Protein Coding gene. Diseases associated with LECT2 include Amyloidosis, Familial Visceral and Colon Small Cell Carcinoma. Among its related pathways are C-MYB transcription factor network. Gene Ontology (GO) annotations related to this gene include identical protein binding.
UniProtKB/Swiss-Prot Summary for LECT2 Gene
Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation (PubMed:9524238). Does not show metalloendopeptidase activity (PubMed:27334921).