Aliases for LDHD Gene
External Ids for LDHD Gene
Previous GeneCards Identifiers for LDHD Gene
The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for LDHD Gene
LDHD (Lactate Dehydrogenase D) is a Protein Coding gene. Diseases associated with LDHD include D-Lactic Aciduria With Gout and Gout. Among its related pathways are Mitochondrial protein import and Metabolic States and Circadian Oscillators. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and oxidoreductase activity, acting on CH-OH group of donors. An important paralog of this gene is D2HGDH.
UniProtKB/Swiss-Prot Summary for LDHD Gene
Involved in D-lactate, but not L-lactate catabolic process.