Aliases for LDB1 Gene
External Ids for LDB1 Gene
Previous GeneCards Identifiers for LDB1 Gene
GeneCards Summary for LDB1 Gene
LDB1 (LIM Domain Binding 1) is a Protein Coding gene. Among its related pathways are Transcriptional misregulation in cancer. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and enzyme binding. An important paralog of this gene is LDB2.
UniProtKB/Swiss-Prot for LDB1 Gene
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity).