Aliases for LCMT1 Gene
External Ids for LCMT1 Gene
Previous GeneCards Identifiers for LCMT1 Gene
LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM, Mar 2008]
GeneCards Summary for LCMT1 Gene
LCMT1 (Leucine Carboxyl Methyltransferase 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and S-adenosylmethionine-dependent methyltransferase activity. An important paralog of this gene is LCMT2.
UniProtKB/Swiss-Prot Summary for LCMT1 Gene
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.