Aliases for LBX1 Gene
External Ids for LBX1 Gene
Previous GeneCards Identifiers for LBX1 Gene
This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by RefSeq, Jul 2008]
GeneCards Summary for LBX1 Gene
LBX1 (Ladybird Homeobox 1) is a Protein Coding gene. Diseases associated with LBX1 include Idiopathic Scoliosis and Split-Hand/Foot Malformation 3. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is LBX2.
UniProtKB/Swiss-Prot Summary for LBX1 Gene
Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.