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Aliases for LARGE2 Gene
Aliases for LARGE2 Gene
External Ids for LARGE2 Gene
- HGNC: 16522
- Entrez Gene: 120071
- Ensembl: ENSG00000165905
- OMIM: 609709
- UniProtKB: Q8N3Y3
Previous HGNC Symbols for LARGE2 Gene
- GYLTL1B
Previous GeneCards Identifiers for LARGE2 Gene
- GC11P045920
Summaries for LARGE2 Gene
GeneCards Summary for LARGE2 Gene
LARGE2 (LARGE Xylosyl- And Glucuronyltransferase 2) is a Protein Coding gene. Diseases associated with LARGE2 include Interstitial Myocarditis and Muscular Dystrophy-Dystroglycanopathy , Type B, 6. Among its related pathways are Metabolism of proteins and Metabolism. An important paralog of this gene is LARGE1.
UniProtKB/Swiss-Prot Summary for LARGE2 Gene
-
Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide. Has a higher activity toward alpha-dystroglycan than LARGE.
Additional gene information for LARGE2 Gene
- HGNC(16522)
- Entrez Gene(120071)
- Ensembl(ENSG00000165905)
- OMIM(609709)
- UniProtKB(Q8N3Y3)
- Open Targets Platform(ENSG00000165905)
- Search for LARGE2 at DataMed
- Search for LARGE2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LARGE2 Gene
Genomics for LARGE2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for LARGE2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around LARGE2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for LARGE2
Genomic Locations for LARGE2 Gene
Genomic Locations for LARGE2 Gene
- chr11:45,921,621-45,929,096
- (GRCh38/hg38)
- Size:
- 7,476 bases
- Orientation:
- Plus strand
- chr11:45,943,172-45,950,647
- (GRCh37/hg19)
- Size:
- 7,476 bases
- Orientation:
- Plus strand
Genomic View for LARGE2 Gene
Genes around LARGE2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11p11.2 by HGNC
- 11p11.2 by Entrez Gene
- 11p11.2 by Ensembl
LARGE2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LARGE2 Gene
Proteins for LARGE2 Gene
-
Protein details for LARGE2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N3Y3-LARG2_HUMAN
- Recommended name:
- LARGE xylosyl- and glucuronyltransferase 2
- Protein Accession:
- Q8N3Y3
- A6NN75
- Q8N8Y6
- Q8NAK3
- Q8WY62
Protein attributes for LARGE2 Gene
- Size:
- 721 amino acids
- Molecular mass:
- 81787 Da
- Cofactor:
- Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
- Quaternary structure:
-
- Interacts with B3GNT1/B4GAT1.
- SequenceCaution:
-
- Sequence=AAG23791.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=BAC03909.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};
Post-translational modifications for LARGE2 Gene
Other Protein References for LARGE2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-GYLTL1B monoclonal antibody
- Novus Biologicals Antibodies for LARGE2
- Invitrogen Antibodies for LARGE2 (AFLGC-LARGE2)
- antibodies-online: Show 9 available GYLTL1B Antibodies ranked by validation data
- Compare Top GYLTL1B Antibodies
-
Quality Products:
Protein Products
-
OriGene Purified Proteins for LARGE2
- Search Origene for MassSpec and Protein Over-expression Lysates for LARGE2
- Origene Custom Protein Services for LARGE2
- Novus Biologicals proteins for LARGE2
- antibodies-online: Show 5 available GYLTL1B Proteins ranked by validation data
- Compare Top GYLTL1B Proteins
-
Quality Products:
No data available for DME Specific Peptides for LARGE2 Gene
Domains & Families for LARGE2 Gene
Gene Families for LARGE2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for LARGE2 Gene
- InterPro:
- Blocks:
-
- Glycosyl transferase, family 8
- ProtoNet:
Suggested Antigen Peptide Sequences for LARGE2 Gene
- GenScript: Design optimal peptide antigens:
-
- Glycosyltransferase-like 1B (LARG2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q8N3Y3UniProtKB/Swiss-Prot:
LARG2_HUMAN :- In the C-terminal section; belongs to the glycosyltransferase 49 family.
- Family:
-
- In the C-terminal section; belongs to the glycosyltransferase 49 family.
- In the N-terminal section; belongs to the glycosyltransferase 8 family.
Function for LARGE2 Gene
Molecular function for LARGE2 Gene
- UniProtKB/Swiss-Prot Function:
- Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide. Has a higher activity toward alpha-dystroglycan than LARGE.
Enzyme Numbers (IUBMB) for LARGE2 Gene
Phenotypes From GWAS Catalog for LARGE2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003824 | catalytic activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 19587235 |
| GO:0015020 | glucuronosyltransferase activity | TAS | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0016757 | transferase activity, transferring glycosyl groups | IBA | 21873635 |
Phenotypes for LARGE2 Gene
- MGI mutant phenotypes for LARGE2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for LARGE2:
Animal Models for LARGE2 Gene
- MGI Knock Outs for LARGE2:
-
- Large2 Large2<tm1(KOMP)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LARGE2 - Select products 50% OFF >
- * LARGE2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for LARGE2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LARGE2
-
Santa Cruz Biotechnology (SCBT) CRISPR for LARGE2
miRNA for LARGE2 Gene
- miRTarBase miRNAs that target LARGE2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LARGE2
- Browse OriGene Inhibitory RNA Products For LARGE2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LARGE2
Clone Products
- Applied Biological Materials (abm): Clones for LARGE2 - Select products 50% OFF >
- * LARGE2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for LARGE2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LARGE2
Cell Line Products
-
Horizon Cell Lines for LARGE2
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for LARGE2 Gene
Localization for LARGE2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for LARGE2 Gene
- Golgi apparatus membrane. Single-pass type II membrane protein.
| Compartment | Confidence |
|---|---|
| golgi apparatus | 5 |
| extracellular | 2 |
| endoplasmic reticulum | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| cytosol | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | -- |
| GO:0005623 | cell | IEA | -- |
| GO:0005794 | Golgi apparatus | IBA | 21873635 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for LARGE2 Gene
Pathways & Interactions for LARGE2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | Mannose type O-glycan biosynthesis | ||
| 3 | Metabolism | ||
| 4 | O-linked glycosylation | ||
Pathways by source for LARGE2 Gene
3 Reactome pathways for LARGE2 Gene
2 KEGG pathways for LARGE2 Gene
UniProtKB/Swiss-Prot Q8N3Y3-LARG2_HUMAN
- Pathway: Protein modification; protein glycosylation.
Interacting Proteins for LARGE2 Gene
Selected Interacting proteins:
Q8N3Y3-LARG2_HUMAN
ENSP00000432869
for LARGE2 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for LARGE2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006486 | protein glycosylation | IEA | -- |
| GO:0006493 | protein O-linked glycosylation | TAS | -- |
| GO:0008152 | metabolic process | IEA | -- |
| GO:0035269 | protein O-linked mannosylation | IDA | 25138275 |
| GO:0046716 | muscle cell cellular homeostasis | ISS | -- |
No data available for SIGNOR curated interactions for LARGE2 Gene
Transcripts for LARGE2 Gene
mRNA/cDNA for LARGE2 Gene
- 3 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000325468 2522 nts (view in UCSC)
- ENST00000401752 2552 nts (view in UCSC)
- ENST00000414027 675 nts (view in UCSC)
- ENST00000525609 566 nts (view in UCSC)
- ENST00000528236 2294 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LARGE2 - Select products 50% OFF >
- * LARGE2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for LARGE2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LARGE2
-
Santa Cruz Biotechnology (SCBT) CRISPR for LARGE2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LARGE2
- Browse OriGene Inhibitory RNA Products For LARGE2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LARGE2
Clone Products
- Applied Biological Materials (abm): Clones for LARGE2 - Select products 50% OFF >
- * LARGE2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for LARGE2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LARGE2
Relevant External Links for LARGE2 Gene
- GeneLoc Exon Structure for
- LARGE2
Expression for LARGE2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Ovary (Reproductive System)
- Pre-Granulosa Cells Primordial Follicle
- Granulosa Cells Primary Follicle
- Gut Tube (Gastrointestinal Tract)
- Kidney (Urinary System)
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LARGE2
mRNA Expression by UniProt/SwissProt for LARGE2 Gene:
Q8N3Y3-LARG2_HUMAN
Tissue specificity:
Widely expressed. Expressed at high level in placenta, pancreas and kidney compared to LARGE. Not expressed in brain.
Evidence on tissue expression from TISSUES for LARGE2 Gene
- Kidney(4.4)
- Nervous system(4.4)
- Skin(2.5)
Primer Products
-
OriGene qPCR primer pairs for LARGE2
-
OriGene qPCR primer pairs and template standards for LARGE2
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for LARGE2 Gene
Orthologs for LARGE2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GYLTL1B 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | GYLTL1B 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | GYLTL1B 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Gyltl1b 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Gyltl1b 30 31 |
|
OneToOne | |
| Large2 17 |
|
||||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | GYLTL1B 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | GYLTL1B 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | GYLTL1B 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | gyltl1b 31 |
|
OneToOne | |
| Worm (Caenorhabditis elegans) |
Secernentea | lge-1 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany |
- Species where no ortholog for LARGE2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
Evolution for LARGE2 Gene
- ENSEMBL:
- Gene Tree for LARGE2 (if available)
- TreeFam:
- Gene Tree for LARGE2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LARGE2: view image
Paralogs for LARGE2 Gene
Variants for LARGE2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LARGE2 Gene
| SNP ID | Clinical significance and condition | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs11038713 | - | p.Arg546Trp | |||
| rs17853729 | - | p.Glu37Lys | |||
| rs2271851 | - | p.Arg677Cys |
Residual Variation Intolerance Score:
84% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.86;
48.22% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LARGE2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- LARGE2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LARGE2 Gene
Disorders for LARGE2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| interstitial myocarditis |
|
|
| muscular dystrophy-dystroglycanopathy , type b, 6 |
|
|
| muscular dystrophy, congenital, lmna-related |
|
|
| ureteral benign neoplasm |
|
|
| walker-warburg syndrome |
|
|
Search LARGE2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for LARGE2
No data available for UniProtKB/Swiss-Prot and Genatlas for LARGE2 Gene
Publications for LARGE2 Gene
- Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies. (PMID: 15958417) Grewal PK … Hewitt JE (Glycobiology 2005) 2 3 4 23
- Localization and functional analysis of the LARGE family of glycosyltransferases: significance for muscular dystrophy. (PMID: 15661757) Brockington M … Muntoni F (Human molecular genetics 2005) 2 3 4 23
- Endogenous glucuronyltransferase activity of LARGE or LARGE2 required for functional modification of α-dystroglycan in cells and tissues. (PMID: 25138275) Inamori K … Campbell KP (The Journal of biological chemistry 2014) 3 4
- Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase. (PMID: 19587235) Bao X … Fukuda M (Proceedings of the National Academy of Sciences of the United States of America 2009) 3 4
- LARGE2 facilitates the maturation of alpha-dystroglycan more effectively than LARGE. (PMID: 15752776) Fujimura K … Narimatsu H (Biochemical and biophysical research communications 2005) 3 4
ExternalLinks
Products for LARGE2 Gene
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for LARGE2
- Search Origene for MassSpec and Protein Over-expression Lysates for LARGE2
- Origene Custom Protein Services for LARGE2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LARGE2
- Browse OriGene Inhibitory RNA Products For LARGE2
- OriGene qPCR primer pairs for LARGE2
- OriGene qPCR primer pairs and template standards for LARGE2
- OriGene CRISPR knockouts for LARGE2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For LARGE2
- Sino Biological Human cDNA Clone for LARGE2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
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- Browse cDNA Clones
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for LARGE2
- Novus Biologicals proteins for LARGE2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for LARGE2 (AFLGC-LARGE2)
- VectorBuilder Custom and pre-made DNA vectors for LARGE2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for LARGE2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for LARGE2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for LARGE2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for LARGE2
- antibodies-online: Show 9 available GYLTL1B Antibodies ranked by validation data
- Compare Top GYLTL1B Antibodies
- Quality Products:
- antibodies-online: Search results for available GYLTL1B related products ranked by validation data
- antibodies-online: Show 5 available GYLTL1B Proteins ranked by validation data
- Compare Top GYLTL1B Proteins
- Quality Products:
- Horizon Cell Lines for LARGE2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LARGE2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LARGE2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for LARGE2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LARGE2
Sources for LARGE2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB