Aliases for L3MBTL2 Gene
External Ids for L3MBTL2 Gene
Previous GeneCards Identifiers for L3MBTL2 Gene
GeneCards Summary for L3MBTL2 Gene
L3MBTL2 (L3MBTL Histone Methyl-Lysine Binding Protein 2) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and SUMOylation. Gene Ontology (GO) annotations related to this gene include histone binding and methylated histone binding. An important paralog of this gene is MBTD1.
UniProtKB/Swiss-Prot Summary for L3MBTL2 Gene
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.