Aliases for L3HYPDH Gene
External Ids for L3HYPDH Gene
Previous HGNC Symbols for L3HYPDH Gene
Previous GeneCards Identifiers for L3HYPDH Gene
The protein encoded by this gene is a dehydratase that converts trans-3-hydroxy-L-proline to delta(1)-pyrroline-2-carboxylate. This enzyme may function to degrade dietary proteins that contain trans-3-hydroxy-L-proline as well as other proteins such as collagen IV. The encoded protein can be converted to an epimerase by changing a threonine to a cysteine at a catalytic site. [provided by RefSeq, Sep 2016]
GeneCards Summary for L3HYPDH Gene
L3HYPDH (Trans-L-3-Hydroxyproline Dehydratase) is a Protein Coding gene. Among its related pathways are Arginine and proline metabolism. Gene Ontology (GO) annotations related to this gene include hydro-lyase activity and trans-L-3-hydroxyproline dehydratase activity.
UniProtKB/Swiss-Prot Summary for L3HYPDH Gene
Catalyzes the dehydration of trans-3-hydroxy-L-proline to Delta(1)-pyrroline-2-carboxylate (Pyr2C). May be required to degrade trans-3-hydroxy-L-proline from the diet and originating from the degradation of proteins such as collagen-IV that contain it.