Aliases for KTN1 Gene
External Ids for KTN1 Gene
Previous GeneCards Identifiers for KTN1 Gene
This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2012]
GeneCards Summary for KTN1 Gene
KTN1 (Kinectin 1) is a Protein Coding gene. Diseases associated with KTN1 include Aplastic Anemia and Attention Deficit-Hyperactivity Disorder. Among its related pathways are Signaling by GPCR and Cytoskeletal Signaling. Gene Ontology (GO) annotations related to this gene include kinesin binding.
UniProtKB/Swiss-Prot Summary for KTN1 Gene
Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin.