Aliases for KRTAP5-8 Gene
External Ids for KRTAP5-8 Gene
Previous GeneCards Identifiers for KRTAP5-8 Gene
GeneCards Summary for KRTAP5-8 Gene
KRTAP5-8 (Keratin Associated Protein 5-8) is a Protein Coding gene. Diseases associated with KRTAP5-8 include Benign Epilepsy With Centrotemporal Spikes. Among its related pathways are Developmental Biology and Keratinization. Gene Ontology (GO) annotations related to this gene include structural constituent of epidermis. An important paralog of this gene is KRTAP5-5.
UniProtKB/Swiss-Prot Summary for KRTAP5-8 Gene
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.