Aliases for KRTAP13-1 Gene
External Ids for KRTAP13-1 Gene
Previous GeneCards Identifiers for KRTAP13-1 Gene
Hair keratins and hair keratin-associated proteins (KAPs), such as KRTAP13-1, are the main structural proteins of hair fibers (Rogers et al., 2002 [PubMed 12359730]).[supplied by OMIM, Mar 2008]
GeneCards Summary for KRTAP13-1 Gene
KRTAP13-1 (Keratin Associated Protein 13-1) is a Protein Coding gene. Diseases associated with KRTAP13-1 include Miliaria Profunda and Miliaria Crystallina. Among its related pathways are Developmental Biology and Keratinization. An important paralog of this gene is KRTAP13-2.
UniProtKB/Swiss-Prot Summary for KRTAP13-1 Gene
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.