Aliases for KRTAP12-1 Gene
External Ids for KRTAP12-1 Gene
Previous GeneCards Identifiers for KRTAP12-1 Gene
GeneCards Summary for KRTAP12-1 Gene
KRTAP12-1 (Keratin Associated Protein 12-1) is a Protein Coding gene. Diseases associated with KRTAP12-1 include Three M Syndrome 1. Among its related pathways are Developmental Biology and Keratinization. An important paralog of this gene is KRTAP12-2.
UniProtKB/Swiss-Prot Summary for KRTAP12-1 Gene
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.