Free for academic non-profit institutions. Other users need a Commercial license
KRTAP11-1 (Keratin Associated Protein 11-1) is a Protein Coding gene. Diseases associated with KRTAP11-1 include Anthracosis. Among its related pathways are Developmental Biology and Keratinization. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is KRTAP13-1.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH21J030903 | Enhancer | 0.3 | Ensembl | 0.3 | -22.8 | -22821 | 1.2 | CEBPB | HSALNG0132608 piR-32214-424 KRTAP11-1 KRTAP19-8 lnc-KRTAP19-8-2 | |
GH21J030893 | Enhancer | 0.2 | FANTOM5 | 0.4 | -12.1 | -12073 | 0.1 | KRTAP21-3 KRTAP19-4 KRTAP6-3 KRTAP13-4 KRTAP15-1 HSALNG0132608 KRTAP11-1 KRTAP19-8 lnc-KRTAP19-8-2 | ||
GH21J030979 | Enhancer | 0.3 | Ensembl | 0.2 | -97.7 | -97721 | 0.2 | ATF2 ATF7 | piR-32214-425 lnc-KRTAP20-3-1 KRTAP19-8 KRTAP11-1 lnc-KRTAP19-8-2 | |
GH21J030995 | Enhancer | 0.4 | FANTOM5 Ensembl | 0.1 | -114.0 | -114046 | 0.4 | KRTAP21-3 LOC105372776 lnc-KRTAP20-3-1 piR-32214-425 KRTAP19-8 lnc-KRTAP19-8-2 KRTAP11-1 | ||
GH21J030996 | Enhancer | 0.2 | Ensembl | 0.1 | -113.6 | -113621 | 0.4 | LOC105372776 lnc-KRTAP20-3-1 piR-32214-425 KRTAP19-8 lnc-KRTAP19-8-2 KRTAP11-1 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 32296183 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005829 | cytosol | TAS | -- |
GO:0005882 | intermediate filament | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Developmental Biology | ||
2 | Keratinization |
.33
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0031424 | keratinization | TAS | -- |
This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | KRTAP11-1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | KRTAP11-1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | KRTAP11-1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Krtap11-1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Krtap11-1 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | KRTAP11-1 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 21 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs9636845 | - |
p.Cys111Ser |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv4424n100 | CNV | gain | 25217958 |
esv3646842 | CNV | loss | 21293372 |
nsv1057467 | CNV | gain | 25217958 |
nsv518454 | CNV | loss | 19592680 |
nsv834077 | CNV | gain | 17160897 |
nsv834078 | CNV | gain | 17160897 |
Disorder | Aliases | PubMed IDs |
---|---|---|
anthracosis |
|
|