Aliases for KRT83 Gene
External Ids for KRT83 Gene
Previous HGNC Symbols for KRT83 Gene
Previous GeneCards Identifiers for KRT83 Gene
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided by RefSeq, Jul 2008]
GeneCards Summary for KRT83 Gene
KRT83 (Keratin 83) is a Protein Coding gene. Diseases associated with KRT83 include Erythrokeratodermia Variabilis Et Progressiva 5 and Monilethrix. Among its related pathways are Developmental Biology and Keratinization. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT81.